Suppr超能文献

深部胸骨伤口感染的治疗选择:胸骨钢板固定术与肌瓣移植术

Therapy options in deep sternal wound infection: Sternal plating versus muscle flap.

作者信息

Grapow Martin, Haug Martin, Tschung Chistopher, Winkler Bernhard, Banerjee Prerana, Heinisch Paul Philipp, Fassl Jens, Reuthebuch Oliver, Eckstein Friedrich

机构信息

Department of Cardiac Surgery, University Hospital, Basel, Switzerland.

Department of Plastic, Reconstructive, Aesthetic, and Hand Surgery, University Hospital, Basel, Switzerland.

出版信息

PLoS One. 2017 Jun 30;12(6):e0180024. doi: 10.1371/journal.pone.0180024. eCollection 2017.

Abstract

BACKGROUND

Management of deep sternal wound infection (DSWI) in cardiac surgical patients still remains challenging. A variety of treatment strategies has been described. Aim of this cohort study was to analyse two different treatment strategies for DSWI: titanium sternal plating system (TSFS) and muscle flap coverage (MFC).

METHODS

Between January 2007 and December 2011, from 3122 patients undergoing cardiac surgery 42 were identified with DSWI and treated with one of the above mentioned strategies. In-hospital data were collected, follow-up performed by telephone and assessment of Quality of Life (QoL) using the SF-12 Health Survey Questionnaire.

RESULTS

20 patients with deep sternal wound infection were stabilized with TSFS and 22 patients treated with MFC. Preoperative demographics and risk factors did not reveal any significant differences. Patients treated with TSFS had a significantly shorter operation time (p<0.05) and shorter hospitalization (p<0.05). A tendency towards lower mortality rate (p = n.s.) and less re-interventions were also noted (plating 0.6 vs. flap 1.17 per patient, n.s.). Quality of Life in the TSFS group for the physical-summary-score was significantly elevated compared to the MFC group (p<0.05). Relating to chest stability and cosmetic result the treatment with TSFS showed superior results, but the usage of MFC gave the patients more freedom in breathing and less chest pain.

CONCLUSION

Our results demonstrate that the use of TSFS is a feasible and safe alternative in DSWI. However, MFC remains an absolutely essential option for complicated DSWI since the amount of perfused tissue can be the key for infection control.

摘要

背景

心脏外科患者深部胸骨伤口感染(DSWI)的管理仍然具有挑战性。已经描述了多种治疗策略。本队列研究的目的是分析DSWI的两种不同治疗策略:钛胸骨接骨板系统(TSFS)和肌瓣覆盖(MFC)。

方法

在2007年1月至2011年12月期间,从3122例接受心脏手术的患者中,确定42例患有DSWI并采用上述策略之一进行治疗。收集住院数据,通过电话进行随访,并使用SF-12健康调查问卷评估生活质量(QoL)。

结果

20例深部胸骨伤口感染患者通过TSFS得到稳定,22例患者接受MFC治疗。术前人口统计学和危险因素未显示任何显著差异。接受TSFS治疗的患者手术时间明显较短(p<0.05),住院时间较短(p<0.05)。还注意到死亡率有降低趋势(p=无统计学意义),再次干预较少(接骨板组每位患者0.6次,皮瓣组每位患者1.17次,无统计学意义)。与MFC组相比,TSFS组的身体综合评分生活质量显著提高(p<0.05)。在胸部稳定性和美容效果方面,TSFS治疗显示出更好的结果,但MFC的使用使患者呼吸更自由,胸痛更少。

结论

我们的结果表明,TSFS的使用是DSWI中一种可行且安全的替代方法。然而,MFC仍然是复杂DSWI的绝对必要选择,因为灌注组织的量可能是控制感染的关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d74/5493354/735a60ff0c95/pone.0180024.g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验