Pastor-Nieto María Antonia, Alcántara-Nicolás Francisco, Melgar-Molero Virginia, Pérez-Mesonero Raquel, Vergara-Sánchez Aránzazu, Martín-Fuentes Adriana, González-Muñoz Patricia, de Eusebio-Murillo Ester
Servicio de Dermatología, Hospital Universitario de Guadalajara , Guadalajara, España; Universidad de Alcalá de Henares, Alcalá de Henares, Madrid, España.
Servicio de Dermatología, Hospital Universitario de Guadalajara , Guadalajara, España; Universidad de Alcalá de Henares, Alcalá de Henares, Madrid, España.
Actas Dermosifiliogr. 2017 Oct;108(8):758-770. doi: 10.1016/j.ad.2017.04.003. Epub 2017 Jun 30.
Preservatives are added to cosmetic, household cleaning, and other industrial products to prevent the growth of microorganisms. Unfortunately, exposure to these substances can cause sensitization.
Between January and June 2015, we analyzed the ingredients of 2300 products commercially available in Spain to identify the frequency of a wide variety of preservatives in different product categories. We analyzed 1093 skin care and cosmetic products sold exclusively in pharmacies (dermocosmetics), 458 household cleaning and personal hygiene and cosmetic products sold in supermarkets, 636 topical medications, and 113 cosmetic products sold in a herbal shop.
Phenoxyethanol, citric acid, sodium benzoate, and potassium sorbate were very common in all the cosmetic product categories. Parabens were present in 16.1% of dermocosmetic products, 14.45% of cosmetic products available in supermarkets, 0.88% of cosmetic products available in the herbal shop, 5.18% of topical medications, and in none of the cleaning products. Isothiazolinones were identified in 2.56% of dermocosmetic products, 18% of cosmetic products in supermarkets, 7.9% of cosmetic products in the herbal shop, 63.63% of household cleaners, and in none of the topical medications. Formaldehyde releasers were detected in 5.76% of dermocosmetic products, 6.42% of cosmetic products sold in supermarkets, 7.96% of cosmetic products sold in the herbal shop, 3.93% of topical medications, and 16.74% of household cleaners.
Evaluation of the presence of preservatives in everyday products allows us to indirectly estimate exposure levels to each one. Measures restricting the use of the most problematic preservatives need to be strengthened.
防腐剂被添加到化妆品、家用清洁产品及其他工业产品中以防止微生物生长。不幸的是,接触这些物质会导致过敏。
2015年1月至6月期间,我们分析了西班牙市场上2300种商品的成分,以确定各类产品中多种防腐剂的使用频率。我们分析了1093种仅在药店销售的皮肤护理和化妆品(皮肤用化妆品)、458种在超市销售的家用清洁、个人卫生及化妆品、636种外用药物以及113种在草药商店销售的化妆品。
苯氧乙醇、柠檬酸、苯甲酸钠和山梨酸钾在所有化妆品类别中都非常常见。对羟基苯甲酸酯类存在于16.1%的皮肤用化妆品中、14.45%的超市化妆品中、0.88%的草药商店化妆品中、5.18%的外用药物中,而在清洁产品中均未检出。异噻唑啉酮类在2.56%的皮肤用化妆品中、18%的超市化妆品中、7.9%的草药商店化妆品中、63.63%的家用清洁剂中被检出,在外用药物中均未检出。在5.76%的皮肤用化妆品中、6.42%的超市销售化妆品中、7.96%的草药商店销售化妆品中、3.93%的外用药物中以及16.74%的家用清洁剂中检测到了甲醛释放剂。
评估日常产品中防腐剂的存在情况使我们能够间接估计对每种防腐剂的接触水平。需要加强限制使用最有问题的防腐剂的措施。