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运动超声心动图评估二尖瓣修复:人工腱索与瓣叶切除术对比

Assessment of Mitral Valve Repair With Exercise Echocardiography: Artificial Chordae vs Leaflet Resection.

作者信息

Ragnarsson Sigurdur, Sjögren Johan, Stagmo Martin, Wierup Per, Nozohoor Shahab

机构信息

Department of Cardiothoracic Surgery, Skane University Hospital, Lund University, Lund, Sweden.

Department of Cardiothoracic Surgery, Skane University Hospital, Lund University, Lund, Sweden.

出版信息

Semin Thorac Cardiovasc Surg. 2017;29(1):25-32. doi: 10.1053/j.semtcvs.2017.01.001. Epub 2017 Jan 10.

Abstract

Mitral valve (MV) repair with artificial chordae (AC) or leaflet resection (LR) is associated with good hemodynamics at rest. The aim of this study was to compare these techniques in terms of exercise capacity and echocardiographic parameters of hemodynamics at rest and peak exercise. We conducted a study in 2015 of 56 patients, who had undergone surgery for degenerative posterior mitral leaflet prolapse between 2005 and 2014 using either AC (n = 24) or LR (n = 32). Clinical data were collected, exercise capacity was measured, and resting echocardiography and peak exercise echocardiography were performed. No significant differences were detected among groups regarding exercise duration or peak exercise workload measured in Watts (W) (AC: 136 ± 43 W and LR: 131 ± 40 W; P = 0.65). The mean mitral gradient at rest was 3.0 ± 1.3 mm Hg in the AC group and 3.0 ± 1.0 mm Hg in the LR group (P = 0.90). The mean MV gradients at peak exercise did not differ significantly between groups (AC: 8.3 ± 3.4 and LR: 11.3 ± 8.7; P = 0.19). Four patients (17%) in the AC group and 1 (3%) in the LR group had systolic anterior motion, P = 0.15. We conclude that both methods of posterior MV leaflet repair were associated with good hemodynamics at rest and peak exercise. The groups had comparable exercise capacity. MV pressure gradients at rest and peak exercise were similar in both groups.

摘要

采用人工腱索(AC)或瓣叶切除术(LR)进行二尖瓣(MV)修复与静息时良好的血流动力学相关。本研究的目的是比较这两种技术在运动能力以及静息和运动峰值时血流动力学的超声心动图参数方面的差异。我们在2015年对56例患者进行了研究,这些患者在2005年至2014年间因退行性二尖瓣后叶脱垂接受了手术,其中采用AC修复的有24例(n = 24),采用LR修复的有32例(n = 32)。收集了临床数据,测量了运动能力,并进行了静息超声心动图和运动峰值超声心动图检查。在运动持续时间或以瓦特(W)为单位测量的运动峰值工作量方面,两组之间未检测到显著差异(AC组:136±43 W,LR组:131±40 W;P = 0.65)。AC组静息时二尖瓣平均压差为3.±1.3 mmHg,LR组为3.0±1.0 mmHg(P = 0.90)。两组在运动峰值时的平均MV压差无显著差异(AC组:8.3±3.4,LR组:11.3±8.7;P = 0.19)。AC组有4例患者(17%)出现收缩期前向运动,LR组有1例患者(3%)出现收缩期前向运动,P = 0.15。我们得出结论,二尖瓣后叶修复的两种方法在静息和运动峰值时均与良好的血流动力学相关。两组的运动能力相当。两组在静息和运动峰值时的MV压力梯度相似。

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