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带扩张髂支的腹主动脉瘤腔内修复术有较高的晚期1b型内漏风险。

EVAR with Flared Iliac Limbs has a High Risk of Late Type 1b Endoleak.

作者信息

Gray D, Shahverdyan R, Reifferscheid V, Gawenda M, Brunkwall J S

机构信息

Clinic of Vascular and Endovascular Surgery, University Hospital of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.

Clinic of Vascular and Endovascular Surgery, University Hospital of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.

出版信息

Eur J Vasc Endovasc Surg. 2017 Aug;54(2):170-176. doi: 10.1016/j.ejvs.2017.05.008. Epub 2017 Jul 5.

Abstract

INTRODUCTION

Re-interventions are still the Achilles' heel of endovascular aneurysm repair (EVAR). Ectatic common iliac arteries (CIA) can be treated with flared iliac limbs but a dilated artery used as sealing zone could increase the risk of a late type 1b endoleak. The aim of the present analysis was to evaluate the risk of late type 1b endoleak after EVAR in patients with CIA limbs ≥20 mm compared with those <20 mm.

METHODS

A retrospective analysis was performed of patients treated by EVAR at the study institution between 2006 and 2012, including patients with available information about the type of iliac stent grafts and a minimum follow-up (FU) of 3 years with contrast enhanced CT, or those that had developed a type 1b endoleak earlier. The cohort was divided into two groups: Group I included iliac limbs with a distal diameter <20 mm, and Group II included all iliac limbs with a distal diameter ≥20 mm.

RESULTS

Of 692 limbs (346 patients), 239 limbs (34.5%) from 129 patients were included in the analysis. Mean CT FU was 53 months, 178 had an iliac stent graft diameter <20 mm (Group I), and 61 a diameter of ≥20 mm (Group II). Mean oversizing for iliac limbs was 17.2% (IQR 14) and there was no case of immediate type 1b endoleak. For the whole group, 18 type 1b endoleaks occurred during FU (7.5%) after a mean of 37.7 months (range 4-96). Eleven of 61 (18%) iliac limbs in Group II developed a type 1b endoleak during FU in contrast to 7/178 (3.9%) in Group I (OR 5.3, 95% CI 1.98-14.59, p = 0,001). The ROC curve analysis indicated a limb diameter of 19 mm as a cutoff value for a higher probability of developing a type 1b endoleak.

CONCLUSION

Patients treated with iliac limbs ≥20 mm had a fivefold higher risk of late (mean 37 months) type 1b endoleak compared with patients treated with a distal iliac limb diameter <20 mm.

摘要

引言

再次干预仍是血管内动脉瘤修复术(EVAR)的致命弱点。扩张的髂总动脉(CIA)可用扩张的髂支进行治疗,但用作密封区的扩张动脉可能会增加晚期1b型内漏的风险。本分析的目的是评估与髂支直径<20mm的患者相比,髂支直径≥20mm的患者在接受EVAR术后发生晚期1b型内漏的风险。

方法

对2006年至2012年在研究机构接受EVAR治疗的患者进行回顾性分析,包括有关于髂支型血管内支架移植物类型的可用信息且通过增强CT进行了至少3年随访(FU)的患者,或那些较早发生1b型内漏的患者。该队列分为两组:第一组包括远端直径<20mm的髂支,第二组包括所有远端直径≥20mm的髂支。

结果

在692条肢体(346例患者)中,分析纳入了129例患者的239条肢体(34.5%)。平均CT随访时间为53个月,178条髂支型血管内支架移植物直径<20mm(第一组),61条直径≥20mm(第二组)。髂支的平均尺寸过大率为17.2%(四分位间距14),且无即刻1b型内漏病例。对于整个组,在平均37.7个月(范围4 - 96个月)的随访期间发生了18例1b型内漏(7.5%)。第二组61条髂支中有11条(18%)在随访期间发生了1b型内漏,而第一组为7/178(3.9%)(比值比5.3,95%可信区间1.98 - 14.59,p = 0.001)。ROC曲线分析表明,肢体直径19mm为发生1b型内漏可能性较高的临界值。

结论

与远端髂支直径<20mm的患者相比,接受髂支直径≥20mm治疗的患者发生晚期(平均37个月)1b型内漏的风险高五倍。

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