Cardiff University, UK.
Cwm Taf University Health Board, UK.
J Atten Disord. 2020 Nov;24(13):1836-1846. doi: 10.1177/1087054717718262. Epub 2017 Jul 8.
The objective of this study was to examine the association between parent mental health (ADHD and depression) and offspring performance on neurocognitive tasks in children with ADHD. The clinical sample consisted of 570 children (85% males, mean age: 10.77 years) with ADHD who completed neurocognitive tasks measuring working memory, attention set-shifting, and motivational deficits. Questionnaire measures were used to assess ADHD and depression symptom presence in parents. Controlling for ADHD severity, children of parents with ADHD had poorer working memory ( = -0.25, 95% confidence interval [CI] [-0.45, -0.07], = .01) and increased errors on the extra dimensional shift stage of the set-shifting task ( = 0.26 95% CI [0.02, 0.50], = .04). Parent depression was not associated with offspring performance on any of the assessed neurocognitive tasks. Children with ADHD who have a parent with ADHD symptom presence are a subgroup of children who may have additional neurocognitive impairments that have potential implications when implementing interventions that target cognition and learning.
本研究旨在探讨父母的心理健康（ADHD 和抑郁）与 ADHD 儿童神经认知任务表现之间的关系。临床样本包括 570 名 ADHD 儿童（85%为男性，平均年龄：10.77 岁），他们完成了测量工作记忆、注意力转换和动机缺陷的神经认知任务。问卷调查用于评估父母的 ADHD 和抑郁症状。在控制 ADHD 严重程度的情况下，父母患有 ADHD 的儿童的工作记忆较差（ = -0.25，95%置信区间 [CI] [-0.45，-0.07]， =.01），并且在注意转换任务的额外维度转换阶段的错误增加（ = 0.26 95% CI [0.02，0.50]， =.04）。父母的抑郁与任何评估的神经认知任务中的子女表现均无关。患有 ADHD 的儿童，如果其父母存在 ADHD 症状，他们可能是存在额外神经认知缺陷的亚组，这在实施针对认知和学习的干预措施时具有潜在影响。
