纹身术提高直肠癌术前放化疗患者小淋巴结检出率和增加淋巴结检出数：一项随机对照临床试验。

Tattooing improves the detection of small lymph nodes and increases the number of retrieved lymph nodes in patients with rectal cancer who receive preoperative chemoradiotherapy: A randomized controlled clinical trial.

机构信息

Department of Surgery, Tokai University, School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.

出版信息

Am J Surg. 2018 Apr;215(4):563-569. doi: 10.1016/j.amjsurg.2017.06.030. Epub 2017 Jul 6.

DOI:10.1016/j.amjsurg.2017.06.030

PMID:28693841

Abstract

BACKGROUND

In rectal cancer who received chemoradiotherapy, the number of Lymph nodes (LNs) required remains unclear. We conducted a randomized controlled trial to determine whether preoperative tattooing increases the number of LNs and enhances the detection rate of metastatic LNs.

METHODS

Eighty patients with rectal cancer who received chemoradiotherapy were randomly assigned to receive no tattooing (C group) or to receive tattooing (T group).

RESULTS

The number of LNs was significantly higher in the T group (13.3 ± 7.4, mean ± SD) than in the C group (8.8 ± 5.9, p < 0.001), however, the number of positive LNs did not differ (0.5 ± 1.3 vs. 0.5 ± 1.1, p = 0.882). The long-axis diameter of LNs was significantly smaller in the T group than in the C group (3.4 ± 1.8 vs. 3.9 ± 2.3 mm, p < 0.001), however, the long-axis diameter of positive LNs did not differ.

CONCLUSIONS

Tattooing increased the number of retrieved LNs by 51%, however, there was no increase in the number of positive LNs.

摘要

背景

在接受放化疗的直肠癌患者中，需要的淋巴结（LNs）数量仍不清楚。我们进行了一项随机对照试验，以确定术前纹身是否会增加淋巴结数量并提高转移性淋巴结的检出率。

方法

80 例接受放化疗的直肠癌患者被随机分配至不纹身（C 组）或纹身（T 组）。

结果

T 组的淋巴结数量（13.3±7.4，平均值±标准差）明显高于 C 组（8.8±5.9，p<0.001），但阳性淋巴结数量无差异（0.5±1.3 与 0.5±1.1，p=0.882）。T 组淋巴结长轴直径明显小于 C 组（3.4±1.8 与 3.9±2.3mm，p<0.001），但阳性淋巴结长轴直径无差异。