完全性与不完全性川崎病的临床表现及心血管结局

Clinical Presentation and Cardiovascular Outcome in Complete versus Incomplete Kawasaki Disease.

作者信息

Shivalingam G, Prashanth G P, Hebbal Kallesh, Aguiar Rodney

机构信息

Department of Pediatrics, Sohar Regional Teaching Hospital, Sohar, Sultanate of Oman. Correspondence to: Dr GP Prashanth, Assistant Professor, Department of Pediatrics, Oman Medical College, PO Box 391, Postal code 321, Sohar, Al-Batinah North Governorate, Sultanate of Oman.

出版信息

Indian Pediatr. 2017 Oct 15;54(10):844-847. doi: 10.1007/s13312-017-1147-6. Epub 2017 Jul 11.

DOI:10.1007/s13312-017-1147-6

PMID:28699614

Abstract

OBJECTIVE

To compare the demographic, clinical, and laboratory features of incomplete and complete presentations of Kawasaki disease.

METHODS

A retrospective review of the electronic case records between January 2000 and December 2015 in a tertiary care referral center of Sohar, Oman.

RESULTS

31 out of 64 children (48.4%) had incomplete presentation. Children with incomplete presentation had higher incidence of skin rash, lymphadenopathy and conjunctivitis. They took a longer time to show clinical response to intravenous immunoglobulin [mean (SD) 52.6 (17.4) h vs 40.1 (16.4) h, P=0.005], and had prolonged hospitalization [mean (SD) 6.2 (2.5) d vs 4.6 (1.7) d, P=0.009].

CONCLUSION

Children with incomplete presentation of Kawasaki disease tend to have prolonged hospitalization but short- and long-term coronary outcomes appear to be similar.

摘要

目的

比较川崎病不完全型和完全型临床表现的人口统计学、临床及实验室特征。

方法

对阿曼苏哈尔一家三级医疗转诊中心2000年1月至2015年12月期间的电子病历进行回顾性分析。

结果

64例儿童中有31例（48.4%）为不完全型表现。不完全型表现的儿童皮疹、淋巴结病和结膜炎的发生率较高。他们对静脉注射免疫球蛋白显示临床反应的时间更长[平均（标准差）52.6（17.4）小时对40.1（16.4）小时，P = 0.005]，住院时间延长[平均（标准差）6.2（2.5）天对4.6（1.7）天，P = 0.009]。