Goddard Thomas D, Huang Conrad C, Meng Elaine C, Pettersen Eric F, Couch Gregory S, Morris John H, Ferrin Thomas E
Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, 94143.
Protein Sci. 2018 Jan;27(1):14-25. doi: 10.1002/pro.3235. Epub 2017 Sep 6.
UCSF ChimeraX is next-generation software for the visualization and analysis of molecular structures, density maps, 3D microscopy, and associated data. It addresses challenges in the size, scope, and disparate types of data attendant with cutting-edge experimental methods, while providing advanced options for high-quality rendering (interactive ambient occlusion, reliable molecular surface calculations, etc.) and professional approaches to software design and distribution. This article highlights some specific advances in the areas of visualization and usability, performance, and extensibility. ChimeraX is free for noncommercial use and is available from http://www.rbvi.ucsf.edu/chimerax/ for Windows, Mac, and Linux.
加州大学旧金山分校的ChimeraX是一款用于可视化和分析分子结构、密度图、三维显微镜图像及相关数据的下一代软件。它应对了前沿实验方法所带来的数据规模、范围及不同类型等方面的挑战,同时还提供了高质量渲染的高级选项(交互式环境光遮蔽、可靠的分子表面计算等)以及软件设计与分发的专业方法。本文重点介绍了在可视化与可用性、性能以及可扩展性等方面的一些具体进展。ChimeraX供非商业使用免费,可从http://www.rbvi.ucsf.edu/chimerax/获取适用于Windows、Mac和Linux的版本。