近红外量子点在生物医学中的应用：现状与展望。
Near infrared quantum dots in biomedical applications: current status and future perspective.
机构信息
School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou, China.
State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University, Changsha, China.
出版信息
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2018 May;10(3):e1483. doi: 10.1002/wnan.1483. Epub 2017 Jul 18.
To address the requirements of biomedical applications including biosensing, bioimaging, and drug delivery, fluorescent nanomaterials served as efficient tools in many cases. Among them, near-infrared quantum dots (NIR QDs) have been used as novel fluorescent labels for their binary advantages of both QDs and NIR light. In this review, through collecting references in recent 10 years, we have introduced basic structures and properties of NIR QDs and summarized the classification and the related synthetic methods. This review also highlights the functionalization and surface bioconjugation of NIR QDs, and their biomedical applications in biosensing, bioimaging, and drug delivery. This article is categorized under: Diagnostic Tools > Diagnostic Nanodevices Diagnostic Tools > In Vitro Nanoparticle-Based Sensing Diagnostic Tools > In Vivo Nanodiagnostics and Imaging.
为满足生物医学应用的需求，包括生物传感、生物成像和药物输送，荧光纳米材料在许多情况下都充当了高效工具。其中，近红外量子点（NIR QDs）因其兼具量子点和近红外光的双重优势，已被用作新型荧光标记物。在这篇综述中，我们通过收集近 10 年来的参考文献，介绍了 NIR QDs 的基本结构和性质，并对其分类和相关合成方法进行了总结。本文还重点介绍了 NIR QDs 的功能化和表面生物偶联及其在生物传感、生物成像和药物输送方面的生物医学应用。本文属于以下分类：诊断工具 > 诊断纳米器件 诊断工具 > 基于体外纳米颗粒的传感 诊断工具 > 体内纳米诊断和成像。
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