在使用醋酸乌利司他治疗巨大子宫平滑肌瘤期间自然受孕
Spontaneous pregnancy during ulipristal acetate treatment of giant uterine leiomyoma.
作者信息
Hrgovic Z, Habek D, Cerkez Habek J, Hrgovic I, Jerkovic Gulin S, Gulin D
机构信息
J.W. Goethe University, Medical School of Frankfurt, Frankfurt, Germany.
"Sveti Duh" University Hospital, Zagreb, Croatia.
出版信息
J Clin Pharm Ther. 2018 Feb;43(1):121-123. doi: 10.1111/jcpt.12590. Epub 2017 Jul 21.
WHAT IS KNOWN AND OBJECTIVE
Ulipristal acetate, a progesterone receptor modulator, pharmacologically inhibits endometrial proliferation and thereby prevents pregnancy. It is primarily used as emergency contraception, but also for the treatment of fibroids in women of reproductive age. There have been no published cases of pregnancy, while on therapy with ulipristal acetate.
CASE DESCRIPTION
In this article, we present a case report of spontaneous pregnancy during ulipristal acetate therapy.
WHAT IS NEW AND CONCLUSION
To our knowledge, this is the first patient with spontaneous conception, while on ulipristal acetate treatment. There were no drug-related complications, and the pregnancy resulted in the delivery of a healthy baby.
已知信息与目的
醋酸乌利司他是一种孕激素受体调节剂，在药理上可抑制子宫内膜增殖，从而防止怀孕。它主要用作紧急避孕药，也用于治疗育龄期女性的子宫肌瘤。目前尚无关于在接受醋酸乌利司他治疗期间怀孕的病例报道。
病例描述
在本文中，我们报告了一例在醋酸乌利司他治疗期间自然受孕的病例。
新发现与结论
据我们所知，这是首例在接受醋酸乌利司他治疗期间自然受孕的患者。未出现与药物相关的并发症，且此次怀孕产下了一名健康婴儿。
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