Sammalkorpi H E, Mentula P, Savolainen H, Leppäniemi A
1 Department of Gastrointestinal Surgery, Helsinki University Central Hospital, Helsinki, Finland.
2 Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Scand J Surg. 2017 Sep;106(3):196-201. doi: 10.1177/1457496916683099. Epub 2017 Mar 1.
Implementation of a clinical risk score into diagnostics of acute appendicitis may provide accurate diagnosis with selective use of imaging studies. The aim of this study was to prospectively validate recently described diagnostic scoring system, Adult Appendicitis Score, and evaluate its effects on negative appendectomy rate.
Adult Appendicitis Score stratifies patients into three groups: high, intermediate, and low risk of appendicitis. The score was implemented in diagnostics of adult patients suspected of acute appendicitis in two university hospitals. We analyzed the effects of Adult Appendicitis Score on diagnostic accuracy, imaging studies, and treatment. The study population was compared with a reference population of 829 patients suspected of acute appendicitis originally enrolled for the study of construction of the Adult Appendicitis Score.
This study enrolled 908 patients of whom 432 (48%) had appendicitis. The score stratified 49% of all appendicitis patients into high-risk group with specificity of 93.3%. In the low-risk group, prevalence of appendicitis was 7%. The histologically confirmed negative appendectomy rate decreased from 18.2% to 8.7%, p<0.001, compared to the original dataset.
Adult Appendicitis Score is a reliable tool for stratification of patients into selective imaging, which results in low negative appendectomy rate.
将临床风险评分应用于急性阑尾炎的诊断,可能通过选择性地使用影像学检查来提供准确诊断。本研究的目的是前瞻性地验证最近描述的诊断评分系统——成人阑尾炎评分,并评估其对阴性阑尾切除率的影响。
成人阑尾炎评分将患者分为三组:阑尾炎高风险、中风险和低风险。该评分应用于两家大学医院疑似急性阑尾炎的成年患者的诊断中。我们分析了成人阑尾炎评分对诊断准确性、影像学检查和治疗的影响。将研究人群与最初纳入成人阑尾炎评分构建研究的829例疑似急性阑尾炎患者的参考人群进行比较。
本研究纳入了908例患者,其中432例(48%)患有阑尾炎。该评分将所有阑尾炎患者的49%分层为高风险组,特异性为93.3%。在低风险组中,阑尾炎患病率为7%。与原始数据集相比,组织学证实的阴性阑尾切除率从18.2%降至8.7%,p<0.001。
成人阑尾炎评分是一种可靠的工具,可将患者分层以进行选择性影像学检查,从而降低阴性阑尾切除率。