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[关于提高睾丸缺血耐受性的动物实验研究]

[Animal experiment studies on improving ischemia tolerance of the testis].

作者信息

Schwaiger R, Stief C, Ziegler M

出版信息

Urologe A. 1986 May;25(3):174-8.

PMID:2874648
Abstract

The reactions of the germinative testicular epithelium after definite ischemia periods were studied in rats. Using heparin the testicular ischemia tolerance has already been prolonged; this can be distinctly improved by adding alphareceptor blockers. The consequences of a 30 min and 2 h period of testicular ischemia are nearly eliminated by the described medicamentous combination. The experimental results show that at present the use of heparin and alpha-receptor blockers seems to be the best way, to extend the ischemia tolerance during autotransplantation of testicles.

摘要

在大鼠身上研究了一定缺血期后生殖性睾丸上皮的反应。使用肝素已经延长了睾丸缺血耐受性;通过添加α受体阻滞剂可使其明显改善。所述药物组合几乎消除了30分钟和2小时睾丸缺血期的后果。实验结果表明,目前使用肝素和α受体阻滞剂似乎是在睾丸自体移植过程中延长缺血耐受性的最佳方法。

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