地高辛特异性免疫Fab成功用于治疗犬重度夹竹桃中毒
Successful use of digoxin-specific immune Fab in the treatment of severe Nerium oleander toxicosis in a dog.
作者信息
Pao-Franco Amaris, Hammond Tara N, Weatherton Linda K, DeClementi Camille, Forney Scott D
机构信息
Departments of Emergency and Critical Care, Veterinary Emergency and Critical Care, Las Vegas, NV, 89147.
Department of Emergency and Critical Care, Tufts Veterinary Emergency Treatments and Specialties, Walpole, MA, 02081.
出版信息
J Vet Emerg Crit Care (San Antonio). 2017 Sep;27(5):596-604. doi: 10.1111/vec.12634. Epub 2017 Jul 29.
OBJECTIVE
To describe a case in which digoxin-specific immune Fab was used successfully in a dog with severe oleander toxicosis secondary to ingesting plant material.
CASE SUMMARY
A 6-year-old intact female Rhodesian Ridgeback mixed breed dog was presented for severe oleander toxicosis and was refractory to all antiarrhythmic therapies and supportive care. Digoxin-specific immune Fab was successful in treating this dog. The dog recovered but suffered ischemic injuries, the long-term effects of which are unknown.
NEW OR UNIQUE INFORMATION PROVIDED
This report describes the successful use of digoxin-specific immune Fab in the treatment of oleander toxicosis in a dog, which has not previously been published in veterinary literature. Oleander poisoning can be associated with permanent cardiac arrhythmias due to the ischemic damage.
目的
描述一例成功使用地高辛特异性免疫Fab治疗因摄入植物材料继发严重夹竹桃中毒的犬的病例。
病例摘要
一只6岁未绝育的雌性罗得西亚脊背犬混种犬因严重夹竹桃中毒就诊，对所有抗心律失常治疗和支持治疗均无反应。地高辛特异性免疫Fab成功治疗了这只犬。该犬康复，但遭受了缺血性损伤，其长期影响尚不清楚。
提供的新的或独特信息
本报告描述了地高辛特异性免疫Fab成功用于治疗犬夹竹桃中毒，此前尚未在兽医文献中发表。夹竹桃中毒可能因缺血性损伤导致永久性心律失常。
Zotero 插件