疲劳——银屑病关节炎中一个被低估的症状。
Fatigue - an underestimated symptom in psoriatic arthritis.
作者信息
Krajewska-Włodarczyk Magdalena, Owczarczyk-Saczonek Agnieszka, Placek Waldemar
机构信息
Department of Rheumatology, The Nicolaus Copernicus Municipal Polyclinical Hospital, Olsztyn, Poland.
Department of Dermatology, Sexually Transmitted Diseases and Clinical Immunology Clinic, University of Warmia and Mazury, Olsztyn, Poland.
出版信息
Reumatologia. 2017;55(3):125-130. doi: 10.5114/reum.2017.68911. Epub 2017 Jul 18.
The nature of fatigue is very complex and involves physiological, psychological and social phenomena at the same time, and the mechanisms leading to occurrence and severity of fatigue are still poorly understood. The condition of chronic inflammation associated with psoriatic arthritis can be regarded as a potential factor affecting development of fatigue. Only a few studies so far have focused on the occurrence of fatigue in psoriatic arthritis. The problem of chronic fatigue is underestimated in everyday clinical practice. Identification and analysis of subjective fatigue components in each patient can provide an objective basis for optimal fatigue treatment in daily practice. This review presents a definition of chronic fatigue and describes mechanisms that may be associated with development of fatigue, highlighting the role of chronic inflammation, selected fatigue measurement methods and relations of fatigue occurrence with clinical aspects of psoriatic arthritis.
疲劳的本质非常复杂，同时涉及生理、心理和社会现象，导致疲劳发生和严重程度的机制仍未得到充分理解。与银屑病关节炎相关的慢性炎症状态可被视为影响疲劳发展的一个潜在因素。迄今为止，只有少数研究关注银屑病关节炎中疲劳的发生情况。在日常临床实践中，慢性疲劳问题被低估了。识别和分析每位患者的主观疲劳成分可为日常实践中优化疲劳治疗提供客观依据。本综述给出了慢性疲劳的定义，描述了可能与疲劳发展相关的机制，强调了慢性炎症的作用、选定的疲劳测量方法以及疲劳发生与银屑病关节炎临床方面的关系。
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