Kawachi Akio, Sakamoto Yusuke, Mouri Shunya, Fukumori Mitsuaki, Kawano Riku, Murakami Takaya, Sonoda Junichiro, Narumi Keiko, Shimodozono Yoshihiro, Etoh Kenji, Chiyotanda Susumu, Furuie Takashi, Sato Keizo, Fukumori Masao, Motoya Toshiro
Graduate School of Pharmaceutical Sciences, Kyushu University of Health and Welfare, Miyazaki, Japan.
Tomitaka Pharmacy, Miyazaki, Japan.
J Pharm Health Care Sci. 2017 Aug 8;3:22. doi: 10.1186/s40780-017-0091-x. eCollection 2017.
As of 2014, community pharmacies in Japan are approved by the Ministry of Health, Labour and Welfare to measure lipid panel, HbA1c, glucose, ALT, AST and γ-GTP, but not to screen for influenza virus. We provided influenza virus screening tests at a community pharmacy to triage people with symptoms suggestive of influenza. Participants were given appropriate advice on how to prevent the spread of and safeguard against influenza. We subsequently evaluated the effects of community pharmacy-based influenza virus screening and prevention measures.
Local residents with symptoms suggestive of influenza participated in this study. Influenza virus screening tests using nasal samples were provided to the pharmacy, and we assessed samples for the presence of influenza virus. The study consisted of a preliminary interview, informed consent, and screening test on Day 1, and mail-in survey on Day 14.
A total 52 local residents participated in the study. The number of participants and influenza virus positive results followed the same trend as the influenza epidemic in the study area. Influenza virus was found in 28.8% of samples. There was no significant difference between the appearance ratios of subjective symptoms among influenza-positive and influenza-negative groups. The percentages of participants who were first screened at the pharmacy, and those who were first screened at a clinic and then tested again at the pharmacy, were 71.2% (37/52) and 28.8% (15/52), respectively. In the latter group, 14 of 15 were negative by screening at the clinic, and one was diagnosed with influenza without testing. Subsequently, 46.8% (7/15) of participants tested positive for influenza by pharmacy-based screening. According to the mail-in survey, all influenza-positive (100%, 7/7) and 35.3% (6/17) of influenza-negative participants visited the clinic after being tested at the community pharmacy; test results between the community pharmacy and clinic were consistent. A total 64.7% (11/17) of symptomatic participants who tested negative recovered spontaneously at home.
Implementation of influenza virus screening followed by provision of appropriate advice for both influenza-positive and influenza-negative participants at the community pharmacy showed a significant effect on improving the health of the local community.
截至2014年,日本的社区药房经厚生劳动省批准可检测血脂、糖化血红蛋白、血糖、谷丙转氨酶、谷草转氨酶和γ-谷氨酰转肽酶,但不能进行流感病毒筛查。我们在一家社区药房提供流感病毒筛查检测,对有流感症状的人群进行分流。并就如何预防流感传播和防范流感向参与者提供了适当建议。随后,我们评估了基于社区药房的流感病毒筛查和预防措施的效果。
有流感症状的当地居民参与了本研究。将使用鼻拭子样本进行的流感病毒筛查检测送到药房,我们对样本进行流感病毒检测。该研究包括第1天的初步访谈、知情同意和筛查检测,以及第14天的邮寄调查。
共有52名当地居民参与了该研究。参与者数量和流感病毒阳性结果与研究区域内的流感流行趋势一致。在28.8%的样本中检测到流感病毒。流感阳性组和流感阴性组主观症状出现率之间无显著差异。首次在药房进行筛查的参与者比例,以及首次在诊所进行筛查然后在药房再次检测的参与者比例分别为71.2%(37/52)和28.8%(15/52)。在后一组中,15人中有14人在诊所筛查为阴性,1人未经检测被诊断为流感。随后,46.8%(7/15)的参与者通过药房筛查检测出流感呈阳性。根据邮寄调查,所有流感阳性参与者(100%,7/7)和35.3%(6/17)的流感阴性参与者在社区药房检测后前往了诊所;社区药房和诊所的检测结果一致。共有64.7%(11/17)检测为阴性的有症状参与者在家中自行康复。
在社区药房实施流感病毒筛查,并为流感阳性和阴性参与者提供适当建议,对改善当地社区健康有显著效果。