Lenighan Yvonne M, Nugent Anne P, Li Kaifeng F, Brennan Lorraine, Walton Janette, Flynn Albert, Roche Helen M, McNulty Breige A
1Nutrigenomics Research Group,School of Public Health, Physiotherapy and Sports Science,UCD Conway Institute,University College Dublin,Belfield,Dublin 4,Republic of Ireland.
2School of Agriculture and Food Science,UCD Institute of Food and Health,University College Dublin,Belfield,Dublin 4,Republic of Ireland.
Br J Nutr. 2017 Aug;118(3):222-228. doi: 10.1017/S0007114517002008.
Evidence suggests that processed red meat consumption is a risk factor for CVD and type 2 diabetes (T2D). This analysis investigates the association between dietary patterns, their processed red meat contributions, and association with blood biomarkers of CVD and T2D, in 786 Irish adults (18-90 years) using cross-sectional data from a 2011 national food consumption survey. All meat-containing foods consumed were assigned to four food groups (n 502) on the basis of whether they contained red or white meat and whether they were processed or unprocessed. The remaining foods (n 2050) were assigned to twenty-nine food groups. Two-step and k-means cluster analyses were applied to derive dietary patterns. Nutrient intakes, plasma fatty acids and biomarkers of CVD and T2D were assessed. A total of four dietary patterns were derived. In comparison with the pattern with lower contributions from processed red meat, the dietary pattern with greater processed red meat intakes presented a poorer Alternate Healthy Eating Index (21·2 (sd 7·7)), a greater proportion of smokers (29 %) and lower plasma EPA (1·34 (sd 0·72) %) and DHA (2·21 (sd 0·84) %) levels (P<0·001). There were no differences in classical biomarkers of CVD and T2D, including serum cholesterol and insulin, across dietary patterns. This suggests that the consideration of processed red meat consumption as a risk factor for CVD and T2D may need to be re-assessed.
有证据表明,食用加工红肉是心血管疾病(CVD)和2型糖尿病(T2D)的一个风险因素。本分析利用2011年全国食物消费调查的横断面数据,调查了786名爱尔兰成年人(18 - 90岁)的饮食模式、其加工红肉摄入量与心血管疾病和2型糖尿病血液生物标志物之间的关联。根据所食用的含肉食品是否含有红肉或白肉以及是否经过加工,将所有含肉食品分为四个食物组(n = 502)。其余食物(n = 2050)分为29个食物组。采用两步法和k均值聚类分析得出饮食模式。评估了营养摄入量、血浆脂肪酸以及心血管疾病和2型糖尿病的生物标志物。总共得出了四种饮食模式。与加工红肉摄入量较低的模式相比,加工红肉摄入量较高的饮食模式的替代健康饮食指数较差(21·2(标准差7·7)),吸烟者比例较高(29%),血浆二十碳五烯酸(EPA)(1·34(标准差0·72)%)和二十二碳六烯酸(DHA)(2·21(标准差0·84)%)水平较低(P<0·001)。不同饮食模式下,心血管疾病和2型糖尿病的经典生物标志物(包括血清胆固醇和胰岛素)没有差异。这表明,将食用加工红肉视为心血管疾病和2型糖尿病的风险因素可能需要重新评估。