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青少年的出生体重及其与血压和营养状况的关系。

Birth weight and its association with blood pressure and nutritional status in adolescents.

机构信息

Universidade Federal de Goiás (UFG), Liga de Hipertensão Arterial, Goiânia, GO, Brazil.

Universidade Federal de Goiás (UFG), Liga de Hipertensão Arterial, Goiânia, GO, Brazil; Brigham & Women's Hospital, Division of Cardiovascular Medicine, Boston, United States.

出版信息

J Pediatr (Rio J). 2018 Mar-Apr;94(2):184-191. doi: 10.1016/j.jped.2017.04.007. Epub 2017 Aug 24.

Abstract

OBJECTIVE

The management of children with low birth weight is not the same in countries with different resources. The authors assessed the association of birth weight with blood pressure and nutritional status in a representative sample of adolescents from a Brazilian state, aiming to identify possible consequences of these differences.

METHODS

A cross-sectional school-based study was conducted with adolescents (12-18 years) enrolled in public and private schools. Birth weight, office blood pressure, home blood pressure measurements, and nutritional status (body mass index, height z-score for the age, and waist circumference) were assessed. The association of birth weight with the outcomes (blood pressure, height, body mass index, and waist circumference) was studied through univariate and multivariable linear regression models.

RESULTS

A total of 829 adolescents with a mean age of 14.6±1.62 years were included; 43.3% were male, and 37.0% from private schools. The prevalence of low birth weight was 8.7%. Mild low height prevalence was higher among those adolescents with low/insufficient birth weight when compared to those with normal/high birth weight (11.7 vs. 4.2%; p<0.001). In the multiple linear regression analysis, for each increase of 100g in birth weight, height increased by 0.28cm (95% CI: 0.18-0.37; p<0.01). Birth weight did not influence office blood pressure and home blood pressure, body mass index, or waist circumference of adolescents.

CONCLUSIONS

Birth weight was directly associated to height, but not associated to blood pressure, body mass index, and waist circumference in adolescents from an urban area of a developing country.

摘要

目的

资源不同的国家,低出生体重儿童的管理方式也不尽相同。作者评估了巴西一个州的代表性青少年样本中出生体重与血压和营养状况之间的关系,旨在确定这些差异可能带来的后果。

方法

进行了一项基于学校的横断面研究,纳入了公立和私立学校的青少年(12-18 岁)。评估了出生体重、诊室血压、家庭血压测量值以及营养状况(体重指数、年龄身高 z 评分和腰围)。通过单变量和多变量线性回归模型研究了出生体重与结局(血压、身高、体重指数和腰围)之间的关系。

结果

共纳入 829 名平均年龄为 14.6±1.62 岁的青少年;其中 43.3%为男性,37.0%来自私立学校。低出生体重的患病率为 8.7%。与出生体重正常/高的青少年相比,出生体重低/不足的青少年低身高的患病率更高(11.7%比 4.2%;p<0.001)。在多元线性回归分析中,出生体重每增加 100g,身高增加 0.28cm(95%CI:0.18-0.37;p<0.01)。出生体重对青少年的诊室血压、家庭血压、体重指数或腰围没有影响。

结论

在发展中国家的城市地区,出生体重与身高直接相关,但与青少年的血压、体重指数和腰围无关。

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