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埃塞俄比亚中部菲切地区医院抗逆转录病毒诊所中接受治疗的HIV感染者抑郁症状相关因素:2012年开展的横断面研究

Factors associated with depressive symptoms in people living with HIV attending antiretroviral clinic at Fitche Zonal Hospital, Central Ethiopia: cross-sectional study conducted in 2012.

作者信息

Yeneabat Tebikew, Bedaso Asres, Amare Tadele

机构信息

Department of Midwifery, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.

School of Nursing and Midwifery, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.

出版信息

Neuropsychiatr Dis Treat. 2017 Aug 8;13:2125-2131. doi: 10.2147/NDT.S131722. eCollection 2017.

Abstract

BACKGROUND

Depression is one of the most common psychiatric disorders with the prevalence rate ranging from 5% to 10% in the general population and about 60% in people living with human immunodeficiency virus (PLHIV). It has been reported to be more common among women living with HIV. In HIV patients, depression can have negative impacts on their quality of life.

OBJECTIVE

This study was aimed at identifying the prevalence of depressive symptoms and associated factors among PLHIV attending the antiretroviral therapy clinic at Fitche Zonal Hospital.

METHODS

It was a cross-sectional study conducted among PLHIV in Fitche Zonal Hospital from February 15 to March 15, 2012. Center for Epidemiologic Studies Depression tool was used to collect data from 390 respondents. Both the bivariate and multivariable logistic regression analyses were carried out and variables with <0.25 in the bivariate logistic regression analysis were entered into multivariable logistic regression analysis and statistical significance was declared at <0.05.

RESULTS

Of the total 390 respondents included in the analysis, the prevalence of depressive symptoms was 76.7%, ranging from mild to moderate (33.6%) to major (43.1%), and the highest proportion was observed among individuals with food insecurity accounting for 287 (79.3%). Food insecurity (adjusted odds ratio [AOR] =3.832 [1.575-9.322]), non-ownership of livestock (AOR =2.17 [1.157-4.104]), and opportunistic infections (AOR =5.20 [1.342-20.156]) were significantly associated with depressive symptoms.

CONCLUSION AND RECOMMENDATIONS

Depressive symptoms were prevalent in PLHIV. Social disparities were important factors of depressive symptoms. Integration of mental health care services with HIV/acquired immune deficiency syndrome-related health care services at all health care levels was necessary. It was recommended that government and non-government organizations should provide assistance to the PLHIV to encourage their involvement in income-generating activities.

摘要

背景

抑郁症是最常见的精神疾病之一,普通人群中的患病率为5%至10%,而感染人类免疫缺陷病毒(PLHIV)的人群中患病率约为60%。据报道,抑郁症在感染HIV的女性中更为常见。在HIV患者中,抑郁症会对他们的生活质量产生负面影响。

目的

本研究旨在确定在菲切地区医院抗逆转录病毒治疗门诊就诊的PLHIV中抑郁症状的患病率及相关因素。

方法

这是一项于2012年2月15日至3月15日在菲切地区医院对PLHIV进行的横断面研究。采用流行病学研究中心抑郁量表工具从390名受访者中收集数据。进行了双变量和多变量逻辑回归分析,双变量逻辑回归分析中P<0.25的变量被纳入多变量逻辑回归分析,P<0.05时具有统计学意义。

结果

在纳入分析的390名受访者中,抑郁症状的患病率为76.7%,从轻度至中度(33.6%)到重度(43.1%)不等,粮食不安全人群中比例最高,占287人(79.3%)。粮食不安全(调整优势比[AOR]=3.832[1.575 - 9.322])、没有牲畜(AOR =2.17[1.157 - 4.104])和机会性感染(AOR =5.20[1.342 - 20.156])与抑郁症状显著相关。

结论与建议

PLHIV中抑郁症状普遍存在。社会差异是抑郁症状的重要因素。在各级医疗保健机构将精神卫生保健服务与HIV/获得性免疫缺陷综合征相关的医疗保健服务整合是必要的。建议政府和非政府组织应为PLHIV提供援助,鼓励他们参与创收活动。

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