黄酮类化合物主要成分在神经退行性疾病病理生理学中的生物有效性——综述
Bio-effectiveness of the main flavonoids of in the pathophysiology of neurodegenerative disorders- a review.
作者信息
Ayoobi Fatemeh, Shamsizadeh Ali, Fatemi Iman, Vakilian Alireza, Allahtavakoli Mohammad, Hassanshahi Gholamhossein, Moghadam-Ahmadi Amir
机构信息
Physiology-Pharmacology Research Center, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Department of Physiology and Pharmacology, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
出版信息
Iran J Basic Med Sci. 2017 Jun;20(6):604-612. doi: 10.22038/IJBMS.2017.8827.
The L. (Yarrow) is a common herb which is widely being used, worldwide. is being used for treatment of many disorders since centuries. It is considered safe for supplemental use and flavonoids such as kaempferol, luteolin and apigenin are of main constituents present in . Most of both antioxidant and anti-inflammatory properties of this herb have been attributed to its flavonoid content. Oxidative and inflammatory processes play important roles in pathogenesis of neurodegenerative diseases. Present review was aimed to review the latest literature evidences regarding application of and/or its three main flavonoid constituents on epilepsy, Alzheimer's disease, multiple sclerosis, Parkinson's disease and stroke.
欧蓍草是一种常见草药，在全球范围内被广泛使用。几个世纪以来，它一直被用于治疗多种疾病。它被认为补充使用是安全的，其主要成分包括山奈酚、木犀草素和芹菜素等黄酮类化合物。这种草药的大部分抗氧化和抗炎特性都归因于其黄酮类化合物含量。氧化和炎症过程在神经退行性疾病的发病机制中起重要作用。本综述旨在回顾关于欧蓍草及其三种主要黄酮类成分在癫痫、阿尔茨海默病、多发性硬化症、帕金森病和中风方面应用的最新文献证据。
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