From the Department of Paediatrics Hospital Santa Maria, Lisbon, Portugal.
Department of Paediatrics, Algarve Hospital Centre, Faro Unit, Portugal.
Pediatr Infect Dis J. 2018 Jun;37(6):e168-e169. doi: 10.1097/INF.0000000000001786.
Infection after implantation of ventriculo-peritoneal shunts is associated with significant morbidity and mortality. We describe a 9-year-old girl with Propionibacterium acnes shunt infection with negative cerebrospinal fluid cultures, diagnosed by broad-range 16S-rRNA gene polymerase chain reaction. This case supports the use of this molecular diagnostic technique in shunt infections, where the offending pathogens are difficult to culture using traditional methods.
脑积水分流术后感染与较高的发病率和死亡率相关。我们描述了一例 9 岁女孩,因Propionibacterium acnes 脑积水分流感染,而脑脊液培养阴性,经广谱 16S-rRNA 基因聚合酶链反应诊断。该病例支持在感染性分流管中使用这种分子诊断技术,因为使用传统方法难以培养出病原体。