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痤疮丙酸杆菌:脑积水分流感染的原因。

Propionibacterium Acnes: Cause of Cerebrospinal Fluid Shunt Infection.

机构信息

From the Department of Paediatrics Hospital Santa Maria, Lisbon, Portugal.

Department of Paediatrics, Algarve Hospital Centre, Faro Unit, Portugal.

出版信息

Pediatr Infect Dis J. 2018 Jun;37(6):e168-e169. doi: 10.1097/INF.0000000000001786.

Abstract

Infection after implantation of ventriculo-peritoneal shunts is associated with significant morbidity and mortality. We describe a 9-year-old girl with Propionibacterium acnes shunt infection with negative cerebrospinal fluid cultures, diagnosed by broad-range 16S-rRNA gene polymerase chain reaction. This case supports the use of this molecular diagnostic technique in shunt infections, where the offending pathogens are difficult to culture using traditional methods.

摘要

脑积水分流术后感染与较高的发病率和死亡率相关。我们描述了一例 9 岁女孩,因Propionibacterium acnes 脑积水分流感染,而脑脊液培养阴性,经广谱 16S-rRNA 基因聚合酶链反应诊断。该病例支持在感染性分流管中使用这种分子诊断技术,因为使用传统方法难以培养出病原体。

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