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2007-2012 年美国俄勒冈州肺外非结核分枝杆菌感染监测。

Surveillance of Extrapulmonary Nontuberculous Mycobacteria Infections, Oregon, USA, 2007-2012.

出版信息

Emerg Infect Dis. 2017 Oct;23(10):1627-1630. doi: 10.3201/eid2310.170845.

Abstract

Limited data are available describing extrapulmonary nontuberculous mycobacteria (NTM) infections in the general population. We describe results from statewide population-based laboratory surveillance in Oregon, USA, during 2007-2012. We defined a case of extrapulmonary NTM infection as >1 isolate from skin/soft tissue, disseminated sites, lymph node, joint, or other sites. The annual incidence of extrapulmonary NTM infection (other than Mycobacterium gordonae) was stable, averaging 1.5 cases/100,000 population. Median age of the 334 patients was 51 years, and 53% of patients were female. Half of cases were caused by M. avium complex, but rapid-growing NTM species accounted for one third of cases. Most extrapulmonary NTM infections are skin/soft tissue. Compared with pulmonary NTM infection, more extrapulmonary infections are caused by rapid-growing NTM species. the designation of NTM as a reportable disease in Oregon in 2014 will result in better detection of changes in the incidence and patterns of disease in the future.

摘要

关于普通人群中肺外非结核分枝杆菌(NTM)感染的资料有限。我们在美国俄勒冈州描述了 2007-2012 年期间全州范围基于人群的实验室监测结果。我们将肺外 NTM 感染定义为从皮肤/软组织、播散部位、淋巴结、关节或其他部位分离出 >1 株。肺外 NTM 感染(除戈登分枝杆菌外)的年发病率稳定,平均为每 100,000 人口 1.5 例。334 名患者的中位年龄为 51 岁,53%的患者为女性。一半的病例由鸟分枝杆菌复合群引起,但快速生长型 NTM 种类占三分之一。大多数肺外 NTM 感染为皮肤/软组织感染。与肺 NTM 感染相比,更多的肺外感染由快速生长型 NTM 引起。2014 年俄勒冈州将 NTM 指定为应报告的疾病,将有助于更好地发现未来疾病发病率和模式的变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea69/5621539/9bd44455aa46/17-0845-F.jpg

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