Zhang Hao-Cong, Zhang Zi-Fang, Wang Zhao-Han, Cheng Jun-Yao, Wu Yun-Chang, Fan Yi-Ming, Wang Tian-Hao, Wang Zheng
Department of Orthopaedics, The General Hospital of Chinese PLA, Beijing, China.
Orthop Surg. 2017 Aug;9(3):304-310. doi: 10.1111/os.12343.
To evaluate the influence of Scoliosis Research Society (SRS)-Schwab sagittal modifiers of pelvic incidence minus lumbar lordosis mismatch (PI-LL) on clinical outcomes for adult degenerative scoliosis (ADS) after long posterior instrumentation and fusion.
This was a single-institute, retrospective study. From 2012 to 2014, 44 patients with ADS who underwent posterior instrumentation and fusion treatment were reviewed. Radiological evaluations were investigated by standing whole spine (posteroanterior and lateral views) X-ray and all radiological measurements, including Cobb's angle, LL, PI, and the grading of vertebral rotation, were performed by two experienced surgeons who were blind to the operations. The patients were divided into three groups based on postoperative PI-LL and the classification of the SRS-Schwab: 0 grade PI-LL (<10°, n = 13); + grade PI-LL (10°-20°, n = 19); and ++ grade PI-LL (>20°, n = 12). The clinical outcomes were assessed according to Japanese Orthopaedic Association (JOA) score, Oswestry Disability Index (ODI), Visual Analog Scale (VAS), Lumbar Stiffness Disability Index (LSDI), and complications. Other characteristic data of patients were also collected, including intraoperative blood loss, operative time, length of hospital stay, complications, number of fusion levels, and number of decompressions.
The mean operative time, blood loss, and hospital stay were 284.5 ± 30.2 min, 1040.5 ± 1207.6 mL, and 14.5 ± 1.9 day. At the last follow-up (2.6 ± 0.6 years), the radiological and functional parameters, except the grading of vertebral rotation, were all significantly improved in comparison with preoperative results (P < 0.05), but it was obvious that an ideal PI-LL (≤10°) was not achieved in some patients. Significant differences were only observed among the three groups in the ODI and LSDI. Patients with + grade PI-LL seemed to have the best surgical outcome compared to those with 0 and ++ grade PI-LL, with the lowest ODI score (+ grade vs 0 grade, 17.3 ± 4.9 vs 26.0 ± 5.4; + grade vs ++ grade, 17.3 ± 4.9 vs 32.4 ± 7.3; P < 0.05) and lower LSDI (+ grade vs 0 grade, 1.6 ± 1.0 vs 3.5 ± 0.5, P < 0.05; + grade vs ++ grade, 1.6 ± 1.0 vs 0.6 ± 0.5, P > 0.05). A Pearson correlation analysis further demonstrated that LSDI was negatively associated with PI-LL. Furthermore, the incidence rate of postoperative complications was lower in patients with + grade PI-LL (1/19, 5.26%) than that in patients with 0 (2/13, 15.4%) and ++ grade PI-LL (3/12, 25%).
Our present study suggest that the ideal PI-LL may be between 10° and 20° in ADS patients after long posterior instrumentation and fusion.
评估脊柱侧弯研究学会(SRS)-施瓦布矢状面参数中骨盆入射角减去腰椎前凸角不匹配(PI-LL)对成人退变性脊柱侧凸(ADS)患者行后路长节段内固定融合术后临床疗效的影响。
这是一项单中心回顾性研究。回顾2012年至2014年期间44例行后路内固定融合治疗的ADS患者。通过站立位全脊柱(正侧位片)X线进行影像学评估,所有影像学测量,包括Cobb角、腰椎前凸角(LL)、骨盆入射角(PI)以及椎体旋转分级,均由两名对手术情况不知情的经验丰富的外科医生进行。根据术后PI-LL及SRS-施瓦布分类将患者分为三组:0级PI-LL(<10°,n = 13);+级PI-LL(10°-20°,n = 19);++级PI-LL(>20°,n = 12)。根据日本骨科学会(JOA)评分、Oswestry功能障碍指数(ODI)、视觉模拟评分(VAS)、腰椎僵硬功能障碍指数(LSDI)及并发症评估临床疗效。还收集了患者的其他特征性数据,包括术中失血量、手术时间、住院时间、并发症、融合节段数及减压节段数。
平均手术时间、失血量及住院时间分别为284.5±30.2分钟、1040.5±1207.6毫升及14.5±1.9天。在末次随访时(2.6±0.6年),与术前结果相比,除椎体旋转分级外,影像学和功能参数均有显著改善(P<0.05),但部分患者未达到理想的PI-LL(≤10°)。三组间仅在ODI和LSDI上存在显著差异。与0级和++级PI-LL患者相比,+级PI-LL患者的手术效果似乎最佳,ODI评分最低(+级vs 0级,17.3±4.9 vs 26.0±5.4;+级vs ++级,17.3±4.9 vs 32.4±7.3;P<0.05),LSDI也较低(+级vs 0级,1.6±1.0 vs 3.5±0.5,P<0.05;+级vs ++级,1.6±1.0 vs 0.6±0.5,P>0.05)。Pearson相关性分析进一步表明LSDI与PI-LL呈负相关。此外,+级PI-LL患者术后并发症发生率(1/19,5.26%)低于0级(2/13,15.4%)和++级PI-LL患者(3/12,25%)。
我们目前的研究表明,对于行后路长节段内固定融合术的ADS患者,理想的PI-LL可能在10°至20°之间。