由……引起的孤立性脑毛霉菌病。 （原文句子不完整，翻译可能不太准确，完整准确翻译需补充完整原文）
Isolated cerebral mucormycosis caused by .
作者信息
Farid Saira, AbuSaleh Omar, Liesman Rachael, Sohail Muhammad Rizwan
机构信息
Department of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA.
Department of Clinical Microbiology, Mayo Clinic, Rochester, Minnesota, USA.
出版信息
BMJ Case Rep. 2017 Oct 4;2017:bcr-2017-221473. doi: 10.1136/bcr-2017-221473.
A 61-year-old man with relapsing chronic lymphocytic leukaemia, status post allogeneic stem cell transplant and multiple chemotherapy regimens presented to the emergency room after suffering a grand mal seizure. His evaluation revealed a 1.5-2 cm ring-enhancing left temporal lobe brain lesion on the CT scan. This brain lesion was resected and the histopathology revealed an invasive fungal organism resembling mucormycosis. Amplification and sequencing of the 28S ribosomal RNA gene identified the organism as The patient was treated with liposomal amphotericin B 5 mg/kg every 24 hours for 4 weeks, and then was transitioned to oral posaconazole. Serial brain imaging at 1 and 3 months, while on therapy, showed significant improvement.
一名61岁男性，患有复发性慢性淋巴细胞白血病，接受异基因干细胞移植及多种化疗方案治疗后，因癫痫大发作被送往急诊室。其CT扫描显示左颞叶有一个1.5 - 2厘米的环形强化脑病变。该脑病变被切除，组织病理学显示为一种类似毛霉菌病的侵袭性真菌生物体。对28S核糖体RNA基因进行扩增和测序，确定该生物体为 患者接受了每24小时5毫克/千克的脂质体两性霉素B治疗，持续4周，然后转为口服泊沙康唑。在治疗期间，第1个月和第3个月的连续脑部影像学检查显示有显著改善。 （原文此处“identified the organism as”后内容缺失）
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