Sen Purnajita, Das Sandeep, Hore Samrat, Bhattacharjee Surajit, Choudhuri Dipayan
Department of Human Physiology, Tripura University (A Central University), Suryamaninagar, Agartala, Tripura, India.
Department of Statistics, Tripura University (A Central University), Suryamaninagar, Agartala, Tripura, India.
J Midlife Health. 2017 Jul-Sep;8(3):110-117. doi: 10.4103/jmh.JMH_116_15.
Cardiometabolic health status of women is a serious public health concern. Markers of body fat content and their distribution are important indicators of cardiometabolic health risk in participants. In addition, socio-demographic status plays a determinant role. The aim of the study was to evaluate the influence of adiposity markers and socio-demographic determinants on various cardiovascular and metabolic risk factors in Indian women.
The study was conducted on 388 women (age 25-65 years) from Tripura, a Northeastern state of India. Various obesity and atherogenic markers such as body mass index (BMI), waist circumference (WC), waist-hip ratio, waist - height ratio, high density lipoprotein-cholesterol (HDL-C)/total cholesterol, HDL-C/low density lipoprotein cholesterol, triglyceride/HDL-C ratio and traditional cardiometabolic risk factors such as high blood pressure, dyslipidemia, and glucose intolerance were evaluated in participant. The socio-demographic status included the level of education and monthly family income.
The cardiometabolic risk in postmenopausal women were higher than premenopausal women. The risk increases with age in both groups. Women with lower educational level and higher income group were found to be prone to higher cardiometabolic risk. Receiver operating characteristics analysis revealed central obesity marked by increased WC was a better predictor of cardiometabolic risk than general obesity marked by increased BMI.
The cardiometabolic risk among both premenopausal and postmenopausal women are associated with central obesity which can be predicted by increased WC in the subject. Socio-demographic status of the participant plays a definitive role in determining cardiometabolic risk in women.
女性的心脏代谢健康状况是一个严重的公共卫生问题。身体脂肪含量及其分布的标志物是参与者心脏代谢健康风险的重要指标。此外,社会人口统计学状况起着决定性作用。本研究的目的是评估肥胖标志物和社会人口统计学决定因素对印度女性各种心血管和代谢危险因素的影响。
该研究对来自印度东北部特里普拉邦的388名女性(年龄25 - 65岁)进行。对参与者评估了各种肥胖和动脉粥样硬化标志物,如体重指数(BMI)、腰围(WC)、腰臀比、腰高比、高密度脂蛋白胆固醇(HDL-C)/总胆固醇、HDL-C/低密度脂蛋白胆固醇、甘油三酯/HDL-C比值,以及传统的心脏代谢危险因素,如高血压、血脂异常和葡萄糖耐量异常。社会人口统计学状况包括教育水平和家庭月收入。
绝经后女性的心脏代谢风险高于绝经前女性。两组风险均随年龄增加。发现教育水平较低且收入较高组的女性更容易出现较高的心脏代谢风险。受试者工作特征分析显示,以腰围增加为特征的中心性肥胖比以BMI增加为特征的全身性肥胖是心脏代谢风险更好的预测指标。
绝经前和绝经后女性的心脏代谢风险均与中心性肥胖相关,中心性肥胖可通过受试者腰围增加来预测。参与者的社会人口统计学状况在确定女性心脏代谢风险方面起着决定性作用。