基于人群的炎症性肠病登记模型：福里经验（1993-2013 年）。
A model of an inflammatory bowel disease population-based registry: The Forlì experience (1993-2013).
机构信息
Department of Gastroenterology and Digestive Endoscopy, AUSL Romagna Morgagni-Pierantoni Hospital, Forlì, Italy.
Department of Gastroenterology and Digestive Endoscopy, AUSL Romagna Morgagni-Pierantoni Hospital, Forlì, Italy.
出版信息
Dig Liver Dis. 2018 Jan;50(1):32-36. doi: 10.1016/j.dld.2017.09.120. Epub 2017 Sep 21.
BACKGROUND AND AIMS
The article presents a population-based registry designed to estimate incidence and prevalence of inflammatory bowel disease (IBD) in the area of Forlì (north-eastern Italy).
METHODS
The registry included all patients with IBD ulcerative colitis (UC) and Crohn's disease (CD) in the Forlì area from 1993 to 2013. A data manager matched records from various sources.
RESULTS
Seven hundred ninety-one patients were registered during the study period, 564 (71.3%) with UC and 227 (28.7%) with CD. The standardized annual incidence rate for UC was 12.8 per 100,000 females (95% CI 11.1-14.4) and 15.7 per 100,000 males (95% CI 13.9-17.5). That of CD was 7.0 per 100,000 for females (95% CI 5.7-8.3) and 5.4 per 100,000 males (95% CI 4.3-6.4). The prevalence of CD and UC on 1 January 2014 was 109.2 per 100,000 inhabitants (95% CI 94.3-124.2) and 266.4 per 100,000 inhabitants (95% CI 243.4-289.7), respectively.
CONCLUSIONS
Although further studies are needed, the data suggest that incidence and prevalence of IBD in Italy are underestimated.
背景与目的
本文介绍了一个基于人群的注册系统，旨在评估意大利东北部福尔利地区炎症性肠病（IBD）的发病率和患病率。
方法
该注册系统纳入了 1993 年至 2013 年福尔利地区所有的 IBD（溃疡性结肠炎[UC]和克罗恩病[CD]）患者。数据管理员匹配了来自不同来源的记录。
结果
在研究期间共登记了 791 例患者，其中 564 例（71.3%）为 UC，227 例（28.7%）为 CD。UC 的标准化年发病率为女性 12.8/10 万（95%CI 11.1-14.4），男性 15.7/10 万（95%CI 13.9-17.5）。CD 的发病率为女性 7.0/10 万（95%CI 5.7-8.3），男性 5.4/10 万（95%CI 4.3-6.4）。2014 年 1 月 1 日时 CD 和 UC 的患病率分别为 109.2/10 万居民（95%CI 94.3-124.2）和 266.4/10 万居民（95%CI 243.4-289.7）。
结论
尽管还需要进一步研究，但这些数据表明意大利的 IBD 发病率和患病率被低估了。
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