Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box #1232, New York, NY, USA.
Clin Geriatr Med. 2017 Nov;33(4):447-457. doi: 10.1016/j.cger.2017.06.001. Epub 2017 Aug 19.
Growth of the segment of the population older than 65 years has led to intensified interest in understanding the biology of aging. This article is focused on age-related alterations in lung structure that produce predictable changes in physiologic function, both at rest and during exercise. Increased insight into the physiology of the healthy aging lung should ultimately lead to improved methods of lung function assessment in the elderly (defined as those older than 65 years) as well as better understanding of the manifestations and possibly even the treatment of geriatric lung disease.
人口中 65 岁以上年龄段的增长,使得人们对理解衰老生物学的兴趣日益浓厚。本文重点关注与年龄相关的肺部结构变化,这些变化会导致静息和运动时生理功能的可预测变化。深入了解健康老年人(定义为年龄大于 65 岁)肺部的生理学,最终应该会改善老年人肺功能评估的方法,并更好地了解老年肺部疾病的表现,甚至可能会改善其治疗方法。