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Low anti-pig antibody levels are key to the success of solid organ xenotransplantation: But is this sufficient?

作者信息

Cooper David K C, Ezzelarab Mohamed B, Hara Hidetaka

机构信息

Xenotransplantation Program, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.

Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, USA.

出版信息

Xenotransplantation. 2017 Nov;24(6). doi: 10.1111/xen.12360. Epub 2017 Oct 25.

Abstract
摘要

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本文引用的文献

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Regulation of Clinical Xenotransplantation-Time for a Reappraisal.
Transplantation. 2017 Aug;101(8):1766-1769. doi: 10.1097/TP.0000000000001683.
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Therapeutic regulation of systemic inflammation in xenograft recipients.
Xenotransplantation. 2017 Mar;24(2). doi: 10.1111/xen.12296. Epub 2017 Mar 12.
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Selection of Patients for Initial Clinical Trials of Solid Organ Xenotransplantation.
Transplantation. 2017 Jul;101(7):1551-1558. doi: 10.1097/TP.0000000000001582.
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Initial in vitro studies on tissues and cells from GTKO/CD46/NeuGcKO pigs.
Xenotransplantation. 2016 Mar;23(2):137-50. doi: 10.1111/xen.12229. Epub 2016 Mar 14.
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Transgenic expression of human CD46: does it reduce the primate T-cell response to pig endothelial cells?
Xenotransplantation. 2015 Nov-Dec;22(6):487-9. doi: 10.1111/xen.12209. Epub 2015 Nov 20.
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Further evidence for sustained systemic inflammation in xenograft recipients (SIXR).
Xenotransplantation. 2015 Sep-Oct;22(5):399-405. doi: 10.1111/xen.12182. Epub 2015 Aug 21.
10
Early graft failure of GalTKO pig organs in baboons is reduced by expression of a human complement pathway-regulatory protein.
Xenotransplantation. 2015 Jul-Aug;22(4):310-6. doi: 10.1111/xen.12176. Epub 2015 Jul 14.

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