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电视辅助胸腔镜手术肺段切除术:一种未得到充分利用的选择?

VATS segmentectomy: an underused option?

作者信息

Mendogni Paolo, Tosi Davide, Rosso Lorenzo, Palleschi Alessandro, Cattaneo Margherita, Mazzucco Alessandra, Nosotti Mario

机构信息

Thoracic Surgery and Lung Transplant Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.

出版信息

J Vis Surg. 2017 Sep 30;3:136. doi: 10.21037/jovs.2017.09.02. eCollection 2017.

Abstract

It is well known that the "gold standard" procedure for surgically resectable early-stage non-small cell lung cancer (NSCLC), is pulmonary lobectomy. Even though sublobar resections (SLR), particularly segmentectomy, seem attractive as an alternative to lobectomy in early stage lung cancers, they are still debated procedures. The aim of this study is to answer to the question: "Is VATS lung segmentectomy an underused option?" To obtain an answer to this query, the authors carried out a review of the "state of the art" as follows: (I) performing a non-systematic review of the literature; (II) analyzing the review articles published; (III) looking at the ongoing studies, the results of which have not yet published; (IV) scanning the technical aspect of lung segmentectomy. After completing the multi-step revision, we can conclude that there is a lack of evidence about the oncological value of segmentectomy in early stage NSCLC. Although VATS segmentectomy is feasible and performed by many thoracic surgeons, it's currently not yet world-wide adopted. Among the trials now being recruited in some countries and, aimed to clarify the role of SLR in the treatment of early stage lung cancer, a European prospective randomized study is advocated to implement the scientific knowledge on this issue.

摘要

众所周知,对于手术可切除的早期非小细胞肺癌(NSCLC),“金标准”手术是肺叶切除术。尽管肺段以下切除术(SLR),尤其是肺段切除术,作为早期肺癌肺叶切除术的替代方案似乎很有吸引力,但它们仍然是存在争议的手术方式。本研究的目的是回答以下问题:“电视辅助胸腔镜手术(VATS)肺段切除术是否是一种未得到充分利用的选择?”为了回答这个问题,作者进行了如下“最新技术水平”的综述:(I)对文献进行非系统综述;(II)分析已发表的综述文章;(III)查看正在进行但结果尚未发表的研究;(IV)审视肺段切除术的技术方面。在完成多步骤修订后,我们可以得出结论,缺乏关于早期NSCLC肺段切除术肿瘤学价值的证据。尽管VATS肺段切除术是可行的,并且许多胸外科医生都在进行,但目前尚未在全球范围内得到采用。在一些国家目前正在招募的、旨在阐明SLR在早期肺癌治疗中作用的试验中,提倡开展一项欧洲前瞻性随机研究,以增进关于这个问题的科学认识。

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Uniportal video-assisted thoracoscopic segmentectomy.单孔电视辅助胸腔镜肺段切除术
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本文引用的文献

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Non-small cell lung cancer: when to offer sublobar resection.非小细胞肺癌:何时进行肺叶下切除
Lung Cancer. 2014 Nov;86(2):115-20. doi: 10.1016/j.lungcan.2014.09.004. Epub 2014 Sep 16.

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