School of Psychology, University of Glasgow, 58 Hillhead Street, Glasgow, Scotland, UK.
Institute of Health and Wellbeing, University of Glasgow, Scotland, UK.
Psychiatry Res. 2018 Jan;259:216-222. doi: 10.1016/j.psychres.2017.09.066. Epub 2017 Sep 28.
Recent evidence suggests that sleep problems are associated with psychotic like experiences including paranoia. However, the mechanisms underpinning this association are not well understood and thus studies modelling hypothesised mediating factors are required. Alexithymia, the inability to recognise and describe emotions within the self may be an important candidate. In two separate studies we sought to investigate factors mediating the relationship between sleep quality and paranoia using a cross-sectional design. Healthy volunteers without a mental health diagnosis were recruited (study 1, N = 401, study 2, N = 402). Participants completed a series of measures assessing paranoia, negative emotions, alexithymia and perceptual anomalies in an online survey. In study 1, regression and mediation analyses showed that the relationship between sleep quality and paranoia was partially mediated by alexithymia, perceptual anomalies and negative affect. In contrast, study 2 found that the relationship between sleep quality and paranoia was fully mediated by negative affect, alexithymia and perceptual anomalies. The link between sleep quality and paranoia is unclear and reasons for discrepant results are discussed. Novel findings in this study include the link between alexithymia and paranoia.
最近的证据表明,睡眠问题与精神病样体验有关,包括妄想。然而,这种关联的机制尚不清楚,因此需要研究模拟假设的中介因素。缺乏识别和描述自身情绪的能力(即述情障碍)可能是一个重要的候选因素。在两项独立的研究中,我们使用横断面设计来研究睡眠质量与妄想之间关系的中介因素。招募了没有心理健康诊断的健康志愿者(研究 1,N=401;研究 2,N=402)。参与者在线调查中完成了一系列评估妄想、负性情绪、述情障碍和知觉异常的测试。在研究 1 中,回归和中介分析表明,睡眠质量与妄想之间的关系部分由述情障碍、知觉异常和负性情绪所介导。相比之下,研究 2 发现,睡眠质量与妄想之间的关系完全由负性情绪、述情障碍和知觉异常所介导。睡眠质量和妄想之间的关系尚不清楚,并且对出现不一致结果的原因进行了讨论。本研究的新发现包括述情障碍与妄想之间的联系。