精神分裂症患者的心理负担和照顾者报告的精神药物不依从性。
Psychological burden and caregiver-reported non-adherence to psychotropic medications among patients with schizophrenia.
机构信息
Department of Pharmacy Practice and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, University of Ghana, P. O. Box LG 43, Legon, Ghana.
Department of Psychology, School of Social Studies, College of Humanities, University of Ghana, P.O. Box LG 84, Legon, Ghana.
出版信息
Psychiatry Res. 2018 Jan;259:289-294. doi: 10.1016/j.psychres.2017.10.034. Epub 2017 Oct 24.
The study examined the association between psychological distress, caregiving burden and caregiver-reported medication adherence in 444 informal family caregivers of patients with schizophrenia. Participants were assessed on the Depression, Anxiety Stress Scale, Zarit Burden Interview and the Medication Adherence Report Scale. Caregivers reported a non-adherence rate of 54.5% among patients with schizophrenia. Poor adherence to antipsychotics was significantly associated with caregiver burden (p < 0.01) and experience of anxiety (p < 0.0001). The burden of caregiving should be considered during the assessment of adherence. The findings suggest a need for culturally appropriate interventions that improve antipsychotic adherence of outpatients with schizophrenia with specific attention to the burden of the caregiver.
这项研究调查了 444 名精神分裂症患者的非专业家庭照顾者的心理困扰、照顾负担和照顾者报告的药物依从性之间的关系。参与者接受了抑郁、焦虑和压力量表、Zarit 负担访谈和药物依从性报告量表的评估。照顾者报告精神分裂症患者的不依从率为 54.5%。抗精神病药物的依从性差与照顾者负担（p < 0.01）和焦虑体验（p < 0.0001）显著相关。在评估依从性时应考虑照顾负担。研究结果表明，需要进行文化上适当的干预，以提高精神分裂症门诊患者的抗精神病药物依从性，特别要注意照顾者的负担。
Zotero 插件