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[因高血压疾病导致的孕产妇死亡。法国孕产妇死亡机密调查结果,2010 - 2012年]

[Maternal deaths due to hypertensive disorders. Results from the French confidential enquiry into maternal deaths, 2010-2012].

作者信息

Dreyfus M, Weber P, Zieleskiewicz L

机构信息

UFR médecine, gynécologie-obstétrique et médecine de la reproduction, CHU de Caen, université de Caen, avenue de la Côte-de-Nacre, 14003 Caen, France.

Gynécologie-obstétrique, centre hospitalier, 87, avenue d'Altkirch, 68051 Mulhouse, France.

出版信息

Gynecol Obstet Fertil Senol. 2017 Dec;45(12S):S38-S42. doi: 10.1016/j.gofs.2017.10.027. Epub 2017 Nov 6.

Abstract

Between 2010 and 2012, the rate of maternal death caused by hypertensive disorders (0,5/100,000 living birth) was reduced by 50% compared to the 2007-2009 period. Hypertensive disorders were responsible from 5% of maternal deaths and from 10% of direct maternal mortality. Eleven deaths happened during the postpartum period but 9 hypertensive complications began before delivery. Seventy percent of these deaths seem to be avoidable. The main causes of suboptimal management were: unappropriated or insufficient obstetrical and anesthetic treatments, undiagnosed HELLP syndrome and subcapsular liver hematoma, delayed treatment. The analysis of these maternal deaths gave the opportunity to stress some major lessons to optimize medical management in case of hypertensive diseases during pregnancy: abdominal symptoms during third trimester of pregnancy lead to search hypertensive disorders; HELLP syndrome with severe anemia indicate to carry out abdominal ultrasound.

摘要

在2010年至2012年期间,与2007 - 2009年期间相比,由高血压疾病导致的孕产妇死亡率(每10万例活产中有0.5例)降低了50%。高血压疾病导致了5%的孕产妇死亡以及10%的孕产妇直接死亡。11例死亡发生在产后阶段,但9例高血压并发症在分娩前就已出现。这些死亡中70%似乎是可以避免的。管理欠佳的主要原因包括:产科和麻醉治疗不当或不足、未诊断出的HELLP综合征和肝包膜下血肿、治疗延迟。对这些孕产妇死亡案例的分析为强调一些重要经验教训提供了契机,以便在孕期高血压疾病的情况下优化医疗管理:妊娠晚期出现腹部症状应排查高血压疾病;伴有严重贫血的HELLP综合征提示应进行腹部超声检查。

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