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老年人身体功能与认知的随龄变化关系。

Age-Varying Relationships Between Physical Function and Cognition in Older Adulthood.

机构信息

Department of Human Development and Family Studies, The Pennsylvania State University, University Park.

出版信息

J Gerontol B Psychol Sci Soc Sci. 2019 Jun 14;74(5):772-784. doi: 10.1093/geronb/gbx126.

Abstract

OBJECTIVES

There are positive relationships between physical and cognitive function in older adulthood; however, the strength of these relationships are inconsistent across studies. Although novel statistical tools provide flexibility to explore age-related differences in relationship magnitude, such methods have not been implemented in gerontological research. This study applied such methods to examine variations in relationship magnitude between physical function and cognition in healthy older adults (N = 2,783).

METHOD

Time-varying effects modeling (TVEM) is an extension of regression that models changes in relationships as a function of time-varying metrics like age. TVEM was used to examine if physical function (Turn 360, grip strength) predicted cognitive performance (memory, processing speed/attention, and reasoning) similarly across adults aged 65-90.

RESULTS

All associations between Turn 360 and all cognitive domains were significant and positive; however, speed of processing had significant magnitude variation across age such that the young-old and the old-old demonstrated the strongest relationships. Associations between grip strength and all cognitive domains significantly strengthened with increased age.

DISCUSSION

Results suggest that depending on the sample age, there may be inconsistencies in the relationships between physical and cognitive performance. Future research should explore these relationships longitudinally to better elucidate discrepant findings.

摘要

目的

在老年人群中,身体功能和认知功能之间存在正相关关系;然而,这些关系的强度在不同研究中并不一致。尽管新的统计工具提供了灵活性,可以探索与年龄相关的关系强度差异,但这些方法尚未在老年学研究中实施。本研究应用这些方法来检查健康老年人(N=2783)中身体功能和认知之间关系强度的变化。

方法

时变效应模型(TVEM)是回归的扩展,它可以根据年龄等时变指标来模拟关系的变化。使用 TVEM 来检验在 65-90 岁的成年人中,身体功能(360 度转身、握力)是否以相同的方式预测认知表现(记忆、处理速度/注意力和推理)。

结果

360 度转身与所有认知领域的所有关联均具有显著的正相关;然而,处理速度在年龄上存在显著的强度变化,即年轻老人和年老老人之间的关系最强。握力与所有认知领域的关联随着年龄的增加而显著增强。

讨论

结果表明,根据样本年龄的不同,身体和认知表现之间的关系可能存在不一致。未来的研究应该从纵向角度探讨这些关系,以更好地阐明不一致的发现。

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