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特应性皮炎中的光疗

Phototherapy in Atopic Dermatitis.

作者信息

Ortiz-Salvador José María, Pérez-Ferriols Amparo

机构信息

Dermatology Department, University General Hospital of Valencia, Av. Tres Cruces n°2, 46014, Valencia, Spain.

出版信息

Adv Exp Med Biol. 2017;996:279-286. doi: 10.1007/978-3-319-56017-5_23.

Abstract

Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases. Currently management of AD includes avoidance of triggering factors, skin care aiming to compensate the skin barrier defects, anti-inflammatory therapy (mostly topical corticosteroids and topical calcineurin inhibitors). When these first-line approaches are unsuccessful, systemic treatment or phototherapy ought to be carried out as next line of defence. Current phototherapy modalities for AD include broadband UVB (290-320 nm), narrowband UVB (311-313 nm), UVA-1 therapy (340-400 nm), UVA therapy plus 8-methoxypsoralens (PUVA), 308 nm excimer laser (EL) and Full spectrum light (FSL).

摘要

特应性皮炎(AD)是最常见的慢性炎症性皮肤病之一。目前AD的治疗包括避免触发因素、旨在弥补皮肤屏障缺陷的皮肤护理、抗炎治疗(主要是外用糖皮质激素和外用钙调神经磷酸酶抑制剂)。当这些一线治疗方法失败时,应进行全身治疗或光疗作为下一道防线。目前用于AD的光疗方式包括宽带UVB(290-320nm)、窄带UVB(311-313nm)、UVA-1疗法(340-400nm)、UVA疗法加8-甲氧基补骨脂素(PUVA)、308nm准分子激光(EL)和全光谱光(FSL)。

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