Go David B, Atashbar Masood Z, Ramshani Zeinab, Chang Hsueh-Chia
Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, Indiana 46556, USA.
Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, Indiana 46556, USA.
Anal Methods. 2017;9(28):4112-4134. doi: 10.1039/C7AY00690J. Epub 2017 Jun 13.
Surface acoustic waves (SAWs), are electro-mechanical waves that form on the surface of piezoelectric crystals. Because they are easy to construct and operate, SAW devices have proven to be versatile and powerful platforms for either direct chemical sensing or for upstream microfluidic processing and sample preparation. This review summarizes recent advances in the development of SAW devices for chemical sensing and analysis. The use of SAW techniques for chemical detection in both gaseous and liquid media is discussed, as well as recent fabrication advances that are pointing the way for the next generation of SAW sensors. Similarly, applications and progress in using SAW devices as microfluidic platforms are covered, ranging from atomization and mixing to new approaches to lysing and cell adhesion studies. Finally, potential new directions and perspectives on the field as it moves forward are offered, with a specific focus on potential strategies for making SAW technologies for bioanalytical applications.
表面声波(SAWs)是在压电晶体表面形成的机电波。由于易于构建和操作,SAW器件已被证明是用于直接化学传感或上游微流体处理及样品制备的通用且强大的平台。本综述总结了用于化学传感和分析的SAW器件开发的最新进展。讨论了SAW技术在气态和液态介质中进行化学检测的应用,以及为下一代SAW传感器指明方向的最新制造进展。同样,涵盖了将SAW器件用作微流体平台的应用和进展,从雾化和混合到用于裂解和细胞粘附研究的新方法。最后,展望了该领域未来可能的新方向和前景,特别关注用于生物分析应用的SAW技术的潜在策略。