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洋甘菊提取物对老年人睡眠质量的影响:一项临床试验。

The effects of chamomile extract on sleep quality among elderly people: A clinical trial.

作者信息

Adib-Hajbaghery Mohsen, Mousavi Seyedeh Nesa

机构信息

Trauma Nursing Research Center, Faculty of Nursing and Midwifery, Kashan University of Medical Sciences, Kashan, Islamic Republic of Iran.

Trauma Nursing Research Center, Faculty of Nursing and Midwifery, Kashan University of Medical Sciences, Kashan, Islamic Republic of Iran.

出版信息

Complement Ther Med. 2017 Dec;35:109-114. doi: 10.1016/j.ctim.2017.09.010. Epub 2017 Oct 13.

Abstract

BACKGROUND

The prevalence of insomnia increases with age. Chamomile is among the medicinal plants which are used as tranquilizer. Yet, there is inadequate experimental and clinical evidence regarding its hypnotic effects. This study sought to evaluate the effects of chamomile extract on sleep quality among elderly people.

DESIGN

A single-blind randomized controlled trial was performed.

SETTING

A convenient sample of sixty elderly people who aged sixty or more and lived in Kahrizak day care nursing home, Karaj, Iran, were randomly allocated to a control and a treatment group. The treatment group received chamomile extract capsules (200mg) twice a day for 28 consecutive days while the control group received wheat flour capsules (200mg) in the same manner. Using the Pittsburgh Sleep Quality Index, sleep quality was assessed immediately before, two weeks after beginning, immediately after the completion, and two weeks after the completion of the intervention. The data were analyzed via the independent-sample t, Chi-square, and Fisher's exact tests as well as the repeated measures analysis of variance.

RESULTS

The means of age in the control and the treatment groups were 70.73±6.44 and 69.36±4.99, respectively. Except for the habitual sleep efficiency component of the Sleep Quality Index, the study groups did not differ significantly from each other at baseline regarding the scores of the other components of the index. Moreover, at baseline, sleep quality in both groups was low, with no statistically significant between-group difference (P=0.639). However, after the intervention, sleep quality in the treatment group was significantly better than the control group (P<0.05).

CONCLUSION

The use of chamomile extract can significantly improve sleep quality among elderly people. Thus, it can be used as a safe modality for promoting elderly people's sleep.

摘要

背景

失眠的患病率随年龄增长而增加。洋甘菊是用作镇静剂的药用植物之一。然而,关于其催眠作用的实验和临床证据不足。本研究旨在评估洋甘菊提取物对老年人睡眠质量的影响。

设计

进行了一项单盲随机对照试验。

地点

从伊朗卡拉季的卡赫里扎克日托疗养院选取了60名60岁及以上的老年人作为便利样本,随机分为对照组和治疗组。治疗组连续28天每天服用两次洋甘菊提取物胶囊(200毫克),而对照组以相同方式服用小麦粉胶囊(200毫克)。使用匹兹堡睡眠质量指数,在干预开始前、开始两周后、干预结束后立即以及干预结束两周后评估睡眠质量。数据通过独立样本t检验、卡方检验、费舍尔精确检验以及重复测量方差分析进行分析。

结果

对照组和治疗组的平均年龄分别为70.73±6.44岁和69.36±4.99岁。除睡眠质量指数的习惯性睡眠效率成分外,两组在基线时该指数其他成分的得分无显著差异。此外,基线时两组的睡眠质量都很低,组间差异无统计学意义(P=0.639)。然而,干预后,治疗组的睡眠质量明显优于对照组(P<0.05)。

结论

使用洋甘菊提取物可显著改善老年人的睡眠质量。因此,它可作为促进老年人睡眠的一种安全方式。

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