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获得性椭圆形红细胞增多症作为伴有环形铁粒幼细胞和多系发育异常的骨髓增生异常综合征的一种表现

Acquired Elliptocytosis as a Manifestation of Myelodysplastic Syndrome with Ring Sideroblasts and Multilineage Dysplasia.

作者信息

Kjelland Jacob D, Dwyre Denis M, Jonas Brian A

机构信息

Department of Internal Medicine, University of California Davis Medical Center, Sacramento, CA 98517, USA.

Department of Pathology, University of California Davis Medical Center, Sacramento, CA 98517, USA.

出版信息

Case Rep Hematol. 2017;2017:3625946. doi: 10.1155/2017/3625946. Epub 2017 Oct 11.

Abstract

Acquired elliptocytosis is a known but rarely described abnormality in the myelodysplastic syndromes (MDS). Here we report the case of an elderly male who was admitted to the hospital with chest pain, dyspnea, and fatigue and was found to be anemic with an elliptocytosis that had only recently been noted on peripheral smears of his blood. After bone marrow biopsy he was diagnosed with MDS with ring sideroblasts and multilineage dysplasia and acquired elliptocytosis. Here we report a rare case of acquired elliptocytosis cooccurring with MDS with ring sideroblasts and multilineage dysplasia.

摘要

获得性椭圆形红细胞增多症是骨髓增生异常综合征(MDS)中一种已知但很少被描述的异常情况。在此,我们报告一例老年男性病例,该患者因胸痛、呼吸困难和疲劳入院,检查发现贫血且外周血涂片近期才发现椭圆形红细胞增多。骨髓活检后,他被诊断为伴有环形铁粒幼细胞和多系发育异常的MDS以及获得性椭圆形红细胞增多症。我们在此报告一例罕见的获得性椭圆形红细胞增多症与伴有环形铁粒幼细胞和多系发育异常的MDS同时发生的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e94/5660754/7b44fae2f823/CRIHEM2017-3625946.001.jpg

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