Lakdawala Nikita, Fedeles Flavia
Department of Dermatology, Medical College of Wisconsin, Milwaukee, WI.
Department of Dermatology Lahey Clinic, Burlington, MA.
Clin Dermatol. 2017 Nov-Dec;35(6):530-540. doi: 10.1016/j.clindermatol.2017.08.004. Epub 2017 Aug 4.
Cutaneous vasculitis, inflammatory destruction of blood vessels, can present with a wide range of clinical and pathologic findings across a number of heterogeneous conditions. Although some vasculitides are present in both children and adults, some important differences exist in clinical presentation, etiology, management, and prognosis in childhood vasculitis versus adult vasculitis. Cutaneous vasculitis is rare in children, and most childhood vasculitides, of which Henoch-Schönlein purpura is the most common, histologically are small vessel leukocytoclastic vasculitis. In children, infectious etiologies are more common than in adults. Childhood cutaneous vasculitis is most often self-limited with a good prognosis, and treatment is mainly supportive. © 2017 Elsevier Inc. All rights reserved.
皮肤血管炎是血管的炎症性破坏,在许多不同的病症中可呈现出广泛的临床和病理表现。虽然有些血管炎在儿童和成人中都有,但儿童血管炎与成人血管炎在临床表现、病因、治疗和预后方面存在一些重要差异。皮肤血管炎在儿童中很少见,大多数儿童血管炎(其中最常见的是过敏性紫癜)在组织学上是小血管白细胞破碎性血管炎。在儿童中,感染性病因比成人更常见。儿童皮肤血管炎通常具有自限性,预后良好,治疗主要是支持性的。© 2017爱思唯尔公司。保留所有权利。