Nahar Abhinav, Shanker Reddy Mukku Shiva, Subramaniyam Bhaskaran Andi, Thippeswamy Harish, Chandra Prabha S, Chaturvedi Santosh Kumar
Centre for Brain Research IISC, Bengaluru, Karnataka, India.
Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.
Indian J Psychol Med. 2017 Sep-Oct;39(5):695-697. doi: 10.4103/IJPSYM.IJPSYM_291_17.
Baclofen is a centrally acting gamma-aminobutyric acid receptor agonist with many therapeutic uses in neurology and psychiatry. An overdose of baclofen is known to cause serious side effects such as encephalopathy, seizures, respiratory depression, and delirium. Association of baclofen with psychosis has also been reported. In this case report, we are highlighting the manifestation of catatonic features in addition to psychosis following baclofen overdose.
巴氯芬是一种中枢性γ-氨基丁酸受体激动剂,在神经病学和精神病学中有多种治疗用途。已知过量服用巴氯芬会导致严重的副作用,如脑病、癫痫发作、呼吸抑制和谵妄。也有报道称巴氯芬与精神病有关。在本病例报告中,我们重点介绍了巴氯芬过量后除精神病外的紧张症特征表现。