甲状腺结节中细针穿刺与冰冻切片诊断价值的比较：一项20年的研究。
The diagnostic value of fine needle aspiration in comparison with frozen section in thyroid nodules: A 20-year study.
作者信息
Siadati Sepideh, Rabiee Seyed Mozafar, Alijanpour Ebrahim, Bayani Mohammad Ali, Nikbakhsh Novin
机构信息
Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
Department. of Anesthesiology, Babol University of Medical Sciences, Babol, Iran.
出版信息
Caspian J Intern Med. 2017 Fall;8(4):301-304. doi: 10.22088/cjim.8.4.301.
BACKGROUND
Fine needle aspiration (FNA) is the most important method in the diagnosis of thyroid nodules before surgery. Recently, the efficiency of FNA in thyroid nodule management has been debatable. On the other hand, intraoperative frozen section (FS) has been used to confirm the diagnosis of FNA and select the proper surgical approach. In this regard, the present study aimed to assess the diagnostic value of FNA as compared to FS in the diagnosis of thyroid nodules.
METHODS
This retrospective study was performed on 69 patients with FNA and FS and histopathological examination from 1993 to 2014 in Babol, northern Iran. FNA was classified into 5 groups: benign (colloid goiter), lymphocytic thyroiditis, follicular lesions, suspicious and malignant, and FS was classified as after benign or malignant. The results of both methods were compared with each other.
RESULTS
This retrospective study was performed on 69 patients with FNA and FS and histopathological examination from 1993 to 2014 in Babol, northern Iran. FNA was classified into 5 groups: benign (colloid goiter), lymphocytic thyroiditis, follicular lesions, suspicious and malignant, and FS was classified as after benign or malignant. The results of both methods were compared with each other.
CONCLUSION
FNA was considered as a simple, less invasive and cost effective method with fewer side effects for evaluation of thyroid nodules. Particulary it had a high sensitivity and specificity in experienced and skilled hands.
背景
细针穿刺抽吸活检（FNA）是术前诊断甲状腺结节最重要的方法。近年来，FNA在甲状腺结节管理中的效率一直存在争议。另一方面，术中冰冻切片（FS）已被用于确认FNA的诊断并选择合适的手术方式。在这方面，本研究旨在评估FNA与FS在甲状腺结节诊断中的诊断价值。
方法
本回顾性研究对1993年至2014年在伊朗北部巴博勒的69例接受FNA、FS及组织病理学检查的患者进行。FNA分为5组：良性（胶样甲状腺肿）、淋巴细胞性甲状腺炎、滤泡性病变、可疑及恶性，FS分为良性或恶性。对两种方法的结果进行相互比较。
结果
本回顾性研究对1993年至2014年在伊朗北部巴博勒的69例接受FNA、FS及组织病理学检查的患者进行。FNA分为5组：良性（胶样甲状腺肿）、淋巴细胞性甲状腺炎、滤泡性病变、可疑及恶性，FS分为良性或恶性。对两种方法的结果进行相互比较。
结论
FNA被认为是一种简单、侵入性小且成本效益高、副作用少的评估甲状腺结节的方法。特别是在经验丰富和技术熟练的医生手中，它具有较高的敏感性和特异性。
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