Wrede Axel, Wiberg Frans, Acosta Stefan
These authors contributed equally to this work.
1 Department of Clinical Sciences, Lund University, Malmö, Sweden.
Vasc Endovascular Surg. 2018 Feb;52(2):115-123. doi: 10.1177/1538574417742762. Epub 2017 Dec 4.
Open repair (OR) for popliteal artery aneurysm (PAA) has recently been challenged by endovascular repair (ER) as the primary choice of treatment. The aim of the present study was to evaluate time trends in treatment modality and compare outcomes between OR and ER among electively operated patients after start of screening in 2010 for abdominal aortic aneurysm (AAA), a disease highly associated with PAA.
Between January 1, 2009, and April 30, 2017, 102 procedures and 36 acute and 66 elective repairs for PAA were identified.
Over time, a trend ( P = .089) for an increasing elective to acute repair ratio of PAA and an increase in elective ER to OR ratio ( P = .003) was found. Among electively repaired PAAs, the ER group was older ( P = .047) and had a higher ankle-brachial index (ABI; P = .044). The ER group had fewer wound infections ( P = .003), fewer major bleeding complications ( P = .046), and shorter in-hospital stay ( P < .001). After 1 year of follow-up, the ER group had a higher rate of major amputations ( P = .037). Amputation-free survival at the end of follow-up did not differ between groups ( P = .68). Among the 17 patients with PAA eligible for AAA screening, 4 (24%) were diagnosed with PAA through the screening program of AAA.
The epidemiology of elective repair of PAA has changed toward increased ER, although ER showed a higher rate of major amputations at 1 year. Confounding was considerable and a randomized trial is needed for evaluation of the best therapeutic option.
腘动脉动脉瘤(PAA)的开放修复术(OR)近来受到血管腔内修复术(ER)的挑战,后者已成为主要的治疗选择。本研究旨在评估治疗方式的时间趋势,并比较2010年开始对腹主动脉瘤(AAA,一种与PAA高度相关的疾病)进行筛查后择期手术患者中OR和ER的治疗效果。
在2009年1月1日至2017年4月30日期间,共确定了102例PAA手术,其中36例为急诊手术,66例为择期修复手术。
随着时间的推移,发现PAA择期与急诊修复比例有增加趋势(P = 0.089),择期ER与OR比例增加(P = 0.003)。在择期修复的PAA患者中,ER组患者年龄较大(P = 0.047),踝肱指数(ABI)较高(P = 0.044)。ER组伤口感染较少(P = 0.003),严重出血并发症较少(P = 0.046),住院时间较短(P < 0.001)。随访1年后,ER组大截肢率较高(P = 0.037)。随访结束时两组的无截肢生存率无差异(P = 0.68)。在17例符合AAA筛查条件的PAA患者中,4例(24%)通过AAA筛查项目被诊断为PAA。
PAA择期修复的流行病学已朝着ER增加的方向转变,尽管ER在1年时大截肢率较高。混杂因素影响较大,需要进行随机试验来评估最佳治疗方案。