Cardiovascular Imaging Unit, ERESA Medical Center, Valencia, Spain.
Department of Medicine, Health Sciences School, CEU-Cardenal Herrera University, Moncada-Valencia, Spain.
J Magn Reson Imaging. 2018 May;47(5):1415-1425. doi: 10.1002/jmri.25894. Epub 2017 Dec 4.
The measurement of myocardial deformation by strain analysis is an evolving tool to quantify regional and global myocardial function.
To assess the feasibility and reproducibility of myocardial strain/strain rate measurements with magnetic resonance feature tracking (MR-FT) in healthy subjects and in patient groups.
Prospective study.
Sixty patients (20 hypertensives with left ventricular (LV) hypertrophy (H); 20 nonischemic dilated cardiomyopathy (D); 20 ischemic heart disease (I); as well as 20 controls (C) were included, 10 men and 10 women in each group.
FIELD STRENGTH/SEQUENCE: A 1.5T MR protocol including steady-state free precession (SSFP) cine sequences in the standard views and late enhancement sequences.
LV volumes, mass, global and regional radial, circumferential, and longitudinal strain/strain rate were measured using CVI42 software. The analysis time was recorded.
Intraobserver and interobserver agreement and intraclass correlation coefficients (ICC) were obtained for reproducibility assessment as well as differences according to gender and group of pertinence.
Strain/strain rate analysis could be achieved in all subjects. The average analysis time was 14 ± 3 minutes. The average intraobserver ICC was excellent (ICC >0.90) for strain and good (ICC >0.75) for strain rate. Reproducibility of strain measurements was good to excellent (ICC >0.75) for all groups of subjects and both genders. Reproducibility of strain measurements was good for basal segments (ICC >0.75) and excellent for middle and apical segments (ICC >0.90). Reproducibility of strain rate measurements was moderate for basal segments (ICC >0.50) and good for middle and apical segments.
MR-FT for strain/strain rate analysis is a feasible and highly reproducible technique. CVI42 FT analysis was equally feasible and reproducible in various pathologies and between genders. Better reproducibility was seen globally for middle and apical segments, which needs further clarification.
3 Technical Efficacy Stage 2 J. Magn. Reson. Imaging 2018;47:1415-1425.
通过应变分析测量心肌变形是一种用于量化区域性和整体心肌功能的新兴工具。
评估磁共振特征追踪（MR-FT）技术测量健康受试者和患者群体心肌应变/应变速率的可行性和可重复性。
前瞻性研究。
60 例患者（20 例高血压伴左心室肥厚（H）；20 例非缺血性扩张型心肌病（D）；20 例缺血性心脏病（I）；以及 20 例对照组（C），每组男女各 10 例。
磁场强度/序列：包括稳态自由进动（SSFP）电影序列的 1.5T MR 方案，以及晚期增强序列。
使用 CVI42 软件测量 LV 容积、质量、整体和局部径向、周向和纵向应变/应变速率。记录分析时间。
获得观察者内和观察者间一致性以及组内相关系数（ICC），以评估重复性，以及根据性别和相关性分组的差异。
所有受试者均能进行应变/应变速率分析。平均分析时间为 14±3 分钟。应变的观察者内 ICC 平均值为优秀（ICC＞0.90），应变速率的 ICC 平均值为良好（ICC＞0.75）。所有受试者和两种性别的应变测量重复性均为良好至优秀（ICC＞0.75）。基底节段应变测量的重复性良好（ICC＞0.75），中段和心尖段应变测量的重复性优秀（ICC＞0.90）。基底节段应变速率测量的重复性为中度（ICC＞0.50），中段和心尖段应变速率测量的重复性为良好。
MR-FT 用于应变/应变速率分析是一种可行且高度可重复的技术。CVI42 FT 分析在各种病理情况下和性别之间同样可行且具有良好的可重复性。中段和心尖段的整体重复性更好，但需要进一步澄清。
3 技术功效 2 级 J. 磁共振成像 2018；47：1415-1425.
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