British Columbia Centre on Substance Use, British Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital, 608-1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada.
Department of Family Medicine, University of British Columbia, St. Paul's Hospital, 608-1081 Burrard Street, Vancouver, BC, V6Z 1Y6, Canada.
Subst Abuse Treat Prev Policy. 2017 Dec 7;12(1):50. doi: 10.1186/s13011-017-0136-z.
Although the initiation of injection drug use has been well characterized among at-risk youth, factors that support or impede cessation of injection drug use have received less attention. We sought to identify socioeconomic factors associated with cessation of injection drug use among street-involved youth.
From September 2005 to May 2015, data were collected from the At-Risk Youth Study (ARYS), a prospective cohort study of street-involved youth in Vancouver, Canada. Multivariate extended Cox regression was utilized to identify socioeconomic factors associated with cessation of injection drug use for six months or longer among youth who were actively injecting.
Among 383 participants, 171 (44.6%) youth reported having ceased injection (crude incidence density 22 per 100 person-years; 95% confidence interval [CI], 19-26) at some point during study follow-up. Youth who had recently dealt drugs (adjusted hazard ration [AHR], 0.50; 95% CI, 0.29-0.87), engaged in prohibited street-based income generation (AHR, 0.41; 95% CI, 0.24-0.69), and engaged in illegal income generating activities (AHR, 0.19; 95% CI, 0.06-0.61) were significantly less likely to report cessation of injection drug use.
Our findings suggest that socioeconomic factors, in particular engagement in prohibited street-based and illegal income generating activities, may pose barriers to ceasing injection drug use among this population. Effort to improve access to stable and secure income, as well as employment opportunities may assist youth in transitioning away from injection drug use.
Our study is not a randomized controlled trial; thus the trial registration is not applicable.
尽管高危青少年的注射吸毒起始情况已得到充分描述,但支持或阻碍其停止注射吸毒的因素却较少受到关注。我们试图确定与街头青少年停止注射吸毒相关的社会经济因素。
2005 年 9 月至 2015 年 5 月期间,从加拿大温哥华街头青少年的前瞻性队列研究——风险青少年研究(ARYS)中收集数据。利用多变量扩展 Cox 回归分析,确定在研究随访期间积极注射毒品的青少年中,与停止注射吸毒六个月或更长时间相关的社会经济因素。
在 383 名参与者中,有 171 名(44.6%)青年报告在研究随访期间的某个时候停止了注射(粗发生率密度为 22/100 人年;95%置信区间 [CI],19-26)。最近从事毒品交易的青少年(调整后的危害比 [AHR],0.50;95%CI,0.29-0.87)、从事被禁止的街头收入来源(AHR,0.41;95%CI,0.24-0.69)和从事非法收入来源(AHR,0.19;95%CI,0.06-0.61)的青少年报告停止注射吸毒的可能性明显较低。
我们的研究结果表明,社会经济因素,特别是从事被禁止的街头收入来源和非法收入来源,可能会阻碍该人群停止注射吸毒。努力改善稳定和安全收入以及就业机会的获取,可能有助于青少年过渡到停止使用注射毒品。
我们的研究不是一项随机对照试验;因此,不适用临床试验注册。