Park Mihwa, Kim Minjeong, Park Jisun, Cho Jinhyun
Department of Internal Medicine, Inha University Hospital, Inha University School of Medicine, Incheon, Korea.
Divison of Hematology-Oncology, Department of Internal Medicine, Inha University Hospital, Inha University School of Medicine, Incheon, Korea.
Yonsei Med J. 2018 Jan;59(1):158-161. doi: 10.3349/ymj.2018.59.1.158.
Radiocontrast media-induced acute severe thrombocytopenia is a very rare complication and potentially life-threatening. Here, we report the case of a 63-year-old male patient with severe acute thrombocytopenia following first exposure to intravenous non-ionic contrast media without immediate allergic reactions. His platelet count dropped from 107000/μL to 2000/μL after six hours of radiocontrast infusion. After administration of corticosteroid and transfusion of platelet concentrates, the platelet count returned gradually to normal within 5 days. To the best of our knowledge, non-ionic contrast media-induced isolated acute severe thrombocytopenia following no signs or symptoms of immediate allergic reaction has never been described.
放射造影剂诱发的急性严重血小板减少症是一种非常罕见的并发症，且可能危及生命。在此，我们报告一例63岁男性患者，首次静脉注射非离子型造影剂后未出现即刻过敏反应，但发生了严重急性血小板减少症。在输注放射造影剂6小时后，他的血小板计数从107000/μL降至2000/μL。给予皮质类固醇并输注血小板浓缩物后，血小板计数在5天内逐渐恢复正常。据我们所知，此前从未有过无即刻过敏反应体征或症状的情况下，非离子型造影剂诱发孤立性急性严重血小板减少症的报道。
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