Grigoriou Marios, Ioannidis Aristeidis, Kofina Konstantinia, Efthimiadis Christoforos
Department of Surgery, Interbalkan Medical Center, Thessaloniki, Greece.
Department of Surgery, Euromedica General Clinic, Thessaloniki, Greece.
J Surg Case Rep. 2017 Nov 29;2017(11):rjx236. doi: 10.1093/jscr/rjx236. eCollection 2017 Nov.
Proctalgia fugax is considered as intermittent anal pain of unknown etiology; a variety of treatments have been used, without, however, permanent results. Injection of botulinum A toxin is recently suggested as an alternative option. We present the case of a woman presenting proctalgia fugax that was untreatable through other current forms of treatment. After two administrations of botulinum A toxin, 80 units and 100 units each, the patient remained asymptomatic on 8-month follow-up control. Botulinum A toxin injection can reduce internal anal sphincter pressure, leading to relief of symptoms, and seems a promising option with minimal morbidity in cases on proctalgia fugax that does not respond to other current treatments.
直肠痛性痉挛被认为是病因不明的间歇性肛门疼痛;已经使用了多种治疗方法,但都没有取得永久性的效果。最近有人建议注射A型肉毒杆菌毒素作为一种替代选择。我们报告一例直肠痛性痉挛的女性病例,该病例通过目前其他治疗方式无法治愈。在两次注射A型肉毒杆菌毒素(每次分别为80单位和100单位)后,患者在8个月的随访中一直无症状。注射A型肉毒杆菌毒素可降低肛门内括约肌压力,从而缓解症状,对于其他现有治疗方法无效的直肠痛性痉挛病例,它似乎是一种有前景且发病率极低的选择。