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Optimizing arginine deprivation for hard-to-treat cancers.

作者信息

Khadeir Ramsay, Szyszko Teresa, Szlosarek Peter W

机构信息

Peter W. Szlosarek: Center for Molecular Oncology, Barts Cancer Institute - a Cancer Research UK Center of Excellence, Queen Mary University of London, John Vane Science Center, London, UK and Barts Health NHS Trust, St Bartholomew's Hospital, London, UK.

出版信息

Oncotarget. 2017 Oct 27;8(57):96468-96469. doi: 10.18632/oncotarget.22099. eCollection 2017 Nov 14.

Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/875a/5722492/f0c76fc4715e/oncotarget-08-96468-g001.jpg

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Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis.
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