Chung Ho Seok, Shin Min-Ho, Park Kwangsung
a Department of Urology , Chonnam National University Medical School , Gwangju , Republic of Korea.
b Department of Preventive Medicine , Chonnam National University Medical School , Gwangju , Republic of Korea.
Aging Male. 2018 Dec;21(4):225-230. doi: 10.1080/13685538.2017.1412423. Epub 2017 Dec 12.
To evaluate the association between handgrip strength and erectile dysfunction (ED) in community-dwelling older men.
This cross-sectional study included 1771 participants of the Dong-gu Study. Handgrip strength was measured with a handheld dynamometer. ED was assessed with the Korean version of the International Index of Erectile Function (IIEF). ED was categorized as none to mild (IIEF-EF scores of 13-30) and moderate to severe (IIEF-EF scores of 0-12). Multivariable logistic regression was conducted with adjustment for potential confounders.
The proportion of men with moderate to severe ED was 48.8%. The age-adjusted ED score increased with increasing quartile of handgrip strength (11.0, 12.4, 13.4, and 14.0 in the lowest, second, third, and highest quartiles, respectively). After adjustment for potential confounders, greater handgrip strength was associated with a lower risk of ED (odds ratio (OR): 0.82 per 5 kg; 95% confidence interval (CI): 0.74-0.90). In addition, a high level of moderate to vigorous physical activity was associated with a lower risk of ED (OR: 0.75; 95% CI: 0.61-0.93).
In this study, aging men with greater handgrip strength had a lower risk of ED. This result suggests that reduced physical functioning may contribute to ED.
评估社区老年男性握力与勃起功能障碍(ED)之间的关联。
这项横断面研究纳入了东关研究的1771名参与者。使用手持测力计测量握力。采用国际勃起功能指数(IIEF)韩语版评估ED。ED分为无至轻度(IIEF-EF评分13 - 30)和中度至重度(IIEF-EF评分0 - 12)。进行多变量逻辑回归并对潜在混杂因素进行调整。
中度至重度ED男性的比例为48.8%。年龄调整后的ED评分随着握力四分位数的增加而升高(最低、第二、第三和最高四分位数分别为11.0、12.4、13.4和14.0)。在对潜在混杂因素进行调整后,握力越大与ED风险越低相关(比值比(OR):每5千克为0.82;95%置信区间(CI):0.74 - 0.90)。此外,高水平的中度至剧烈身体活动与较低的ED风险相关(OR:0.75;95%CI:0.61 - 0.93)。
在本研究中,握力较大的老年男性患ED的风险较低。这一结果表明身体功能下降可能导致ED。