Stoneham M D, Von Kier S, Harvey L, Murphy M
Nuffield Division of Anaesthetics, John Radcliffe Hospital, Oxford, UK.
Haemostasis and Blood Conservation Service, John Radcliffe Hospital, Oxford, UK.
Transfus Med. 2018 Aug;28(4):290-297. doi: 10.1111/tme.12495. Epub 2017 Dec 15.
To investigate the impact of a dedicated cell salvage practitioner team on blood loss and allogeneic transfusion in abdominal aortic aneurysm (AAA) surgery.
Cell salvage reduces allogeneic transfusion in AAA surgery, but is commonly performed by the anaesthetic nurse. At our hospital, a dedicated patient blood management practitioner is present for all elective open AAA repairs.
METHODS/MATERIALS: Data were collected on 171 AAA patients operated on at the John Radcliffe Hospital, Oxford over a 3-year period, looking at the Patient Blood Management processes, including: blood loss, cell salvage, near-patient testing (thrombelastography) and transfusion rates of allogeneic blood products.
Blood loss ranged from 3-108% of estimated blood volume (EBV) (median 25% = 1500 mL). In seven patients who lost 70-110% of their EBV, none reached the thrombelastography intervention threshold for R time (11 min) or MA (48 mm) despite such massive blood loss. Overall, only 7/171 (4%) patients received intra-operative allogeneic blood, all of whom had a mean baseline haemoglobin concentration < 106 g L (median 98, range 95-105 g L ). In terms of other blood products, only 4/171 (2·3%) received one unit of platelets each intra-operatively. None received FFP or cryoprecipitate.
Such low levels of allogeneic transfusion have not been reported previously. We hypothesise that this is due to the additional blood management contributions of the specialised cell salvage practitioners and collaboration with the rest of the vascular surgical team. These results support the development of pre-operative anaemia clinics. Overall the service runs at a profit to the trust.
研究专业的自体血回收从业者团队对腹主动脉瘤(AAA)手术中失血及异体输血的影响。
自体血回收可减少AAA手术中的异体输血,但通常由麻醉护士操作。在我们医院,所有择期开放性AAA修复手术都有专业的患者血液管理从业者参与。
方法/材料:收集了牛津约翰拉德克利夫医院3年内接受手术的171例AAA患者的数据,观察患者血液管理流程,包括:失血情况、自体血回收、床旁检测(血栓弹力图)及异体血制品的输血率。
失血量为估计血容量(EBV)的3%-108%(中位数25% = 1500 mL)。7例失血量达EBV的70%-110%的患者,尽管失血量大,但均未达到血栓弹力图R时间(11分钟)或MA(48毫米)的干预阈值。总体而言,仅7/171(4%)例患者术中接受了异体血,所有这些患者的平均基线血红蛋白浓度<106 g/L(中位数98,范围95-105 g/L)。在其他血液制品方面,仅4/171(2.3%)例患者术中各接受了1单位血小板。无人接受新鲜冰冻血浆或冷沉淀。
此前尚未报道过如此低水平的异体输血情况。我们推测这是由于专业自体血回收从业者在血液管理方面的额外贡献以及与血管外科团队其他成员的协作。这些结果支持术前贫血门诊的开展。总体而言,该服务对医院信托而言是盈利的。