Wang Yang, Tong Yao, Xu Xu, Zhang Lei
College of Chemistry, Liaoning University, Shenyang 110036, China.
College of Chemistry, Liaoning University, Shenyang 110036, China.
J Chromatogr A. 2018 Jan 19;1533:1-9. doi: 10.1016/j.chroma.2017.12.021. Epub 2017 Dec 11.
A unique 3D porous Cu@graphitic octahedron carbon cages were constructed by rapid room-temperature synthesis of a Cu-based metal-organic framework (MOF) with further pyrolysis in N, which exhibited good enrichment ability for four fluoroquinolones (FQs) due to their superior chemical affinities to the target analytes. Applied Cu@graphitic octahedron carbon cages as adsorbent, a dispersive solid phase extraction (DSPE) method combined with HPLC was developed for detecting four FQs in real samples. Various parameters affecting residues FQs extraction efficiency were inquired in more detail. Under optimal conditions, the extraction recoveries of four FQs in chicken muscle, fish tissue, seawater and river water samples were in the range of 81.3∼104.3% and the RSDs (n = 5) were less than 5.2%. This method was successfully used to the determination of FQs in real samples.
通过在室温下快速合成基于铜的金属有机框架（MOF）并在氮气中进一步热解，构建了独特的三维多孔铜@石墨八面体碳笼，由于其对目标分析物具有优异的化学亲和力，该碳笼对四种氟喹诺酮（FQs）表现出良好的富集能力。将铜@石墨八面体碳笼用作吸附剂，开发了一种结合高效液相色谱（HPLC）的分散固相萃取（DSPE）方法，用于检测实际样品中的四种FQs。更详细地探究了影响残留FQs萃取效率的各种参数。在最佳条件下，鸡肉、鱼肉、海水和河水样品中四种FQs的萃取回收率在81.3%至104.3%之间，相对标准偏差（n = 5）小于5.2%。该方法成功用于实际样品中FQs的测定。
