Ng H K, Tse C C, Lo S T
Department of Morbid Anatomy, Chinese University of Hong Kong.
Histopathology. 1989 Jan;14(1):1-9. doi: 10.1111/j.1365-2559.1989.tb02109.x.
Nine cases of microcystic meningiomas, a distinct morphological variant of meningiomas, are reported. They are characterized by a vacuolated and myxomatous histological appearance with multiple cystic spaces lined by stellate-shaped tumour cells. Immunohistochemically, they shared a similar pattern of positive staining for epithelial membrane antigen and vimentin with other meningiomas. Their unusual histological features might lead to problems in differential diagnosis from other intracranial tumours, including schwannomas, chordomas, astrocytomas and angioblastic meningiomas.
本文报告了9例微囊性脑膜瘤,这是一种独特的脑膜瘤形态学变异型。其特征为组织学上呈空泡状和黏液瘤样外观,有多个由星状肿瘤细胞衬里的囊腔。免疫组化显示,它们与其他脑膜瘤在上皮膜抗原和波形蛋白的阳性染色模式上相似。其不寻常的组织学特征可能导致在与其他颅内肿瘤(包括神经鞘瘤、脊索瘤、星形细胞瘤和血管母细胞性脑膜瘤)的鉴别诊断中出现问题。