里斯本的转化生长因子β超家族：探索发育与疾病

The TGFβ superfamily in Lisbon: navigating through development and disease.

作者信息

Christian Jan L, Heldin Carl-Henrik

机构信息

Department of Neurobiology and Anatomy and Internal Medicine, Division of Hematology and Hematologic Malignancies, University of Utah, School of Medicine, Salt Lake City, UT 94132, USA

Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Box 582, Uppsala University, SE-751 23 Uppsala, Sweden.

出版信息

Development. 2017 Dec 15;144(24):4476-4480. doi: 10.1242/dev.159756.

DOI:10.1242/dev.159756

PMID:29254990

Abstract

The 10th FASEB meeting 'The TGFβ Superfamily: Signaling in Development and Disease' took place in Lisbon, Portugal, in July 2017. As we review here, the findings presented at the meeting highlighted the important contributions of TGFβ family signaling to normal development, adult homeostasis and disease, and also revealed novel mechanisms by which TGFβ signals are transduced.

摘要

第十届美国实验生物学联合会（FASEB）会议“转化生长因子β（TGFβ）超家族：发育与疾病中的信号传导”于2017年7月在葡萄牙里斯本举行。正如我们在此回顾的那样，会议上展示的研究结果突出了TGFβ家族信号传导对正常发育、成体稳态和疾病的重要贡献，同时也揭示了TGFβ信号转导的新机制。